Utilization of a 3D printer to fabricate boluses used for electron therapy of skin lesions of the eye canthi

Łukowiak, Magdalena; Jezierska, K; Boehlke, Marek; Więcko, Marzena; Łukowiak, Adam; Podraza, Wojciech; Lewocki, Mirosław; Masojć, Bartłomiej; Falco, Michał

doi:10.1002/acm2.12013

Cited by 50 publications

(9 citation statements)

References 28 publications

(37 reference statements)

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“…Common filament materials for AM-bolus include acrylonitrile butadiene styrene (ABS) [34,44] and polylactic-acid (PLA) [45,46]. Due to non-toxicity and biocompatibility with comparable treatment planning system (TPS) dose profiles, PLA is currently preferred by clinicians for clinical bolus use [47].…”

Section: Bolusmentioning

confidence: 99%

Additive manufacturing in radiation oncology: a review of clinical practice, emerging trends and research opportunities

Tino

Leary

Yeo

et al. 2020

Int. J. Extrem. Manuf.

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The additive manufacturing (AM) process plays an important role in enabling cross-disciplinary research in engineering and personalised medicine. Commercially available clinical tools currently utilised in radiotherapy are typically based on traditional manufacturing processes, often leading to non-conformal geometries, time-consuming manufacturing process and high costs. An emerging application explores the design and development of patient-specific clinical tools using AM to optimise treatment outcomes among cancer patients receiving radiation therapy. In this review, we: • highlight the key advantages of AM in radiotherapy where rapid prototyping allows for patient-specific manufacture • explore common clinical workflows involving radiotherapy tools such as bolus, compensators, anthropomorphic phantoms, immobilisers, and brachytherapy moulds; and • investigate how current AM processes are exploited by researchers to achieve patient tissue-like imaging and dose attenuations. Finally, significant AM research opportunities in this space are highlighted for their future advancements in radiotherapy for diagnostic and clinical research applications.

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Section: Bolusmentioning

confidence: 99%

Additive manufacturing in radiation oncology: a review of clinical practice, emerging trends and research opportunities

Tino

Leary

Yeo

et al. 2020

Int. J. Extrem. Manuf.

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“…Previous study [13] has proposed the use of 3D-printed plastic objects for this purpose and investigated the properties of electron beam interaction with such samples. Another study [14] compared 3D-printed boluses with standard boluses. The results indicate the effectiveness of using plastic materials for bolus manufacturing [13,14].…”

Section: Introductionmentioning

confidence: 99%

“…Another study [14] compared 3D-printed boluses with standard boluses. The results indicate the effectiveness of using plastic materials for bolus manufacturing [13,14].…”

Section: Introductionmentioning

confidence: 99%

Numerical simulation of electron beam depth dose distribution in water phantom passed through modified plastic materials

Grigorieva,

Bulavskaya,

Bushmina

et al. 2023

J. Phys.: Conf. Ser.

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The aim of the study is to evaluate the feasibility of using modified plastics for 3D printing of boluses for electron beam therapy. Filaments for 3D printing made from plastic materials with an admixture of copper were studied. Test samples were made from these filaments and investigated. Mathematical models of such products were created based on the obtained data. The thicknesses of the boluses made from each modified material were calculated to achieve the same electron beam depth dose distribution in the water phantom as natural plastic. Using a the developed model of a therapeutic electron beam and newly created models of test object materials, the electron beam depth dose distributions in the water phantom that passed through the materials under study were obtained in bolus geometry. The results of the work demonstrate the potential of using modified plastics for creating forming elements in electron beam therapy. The application of this plastic samples for electron beam shaping with individual configuration allows to modify the irradiation field based on the clinical tasks quickly and efficiently and to increase the effectiveness of electron beam radiotherapy procedures.

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“…The papers [8][9][10][11] proposes a method of forming clinical electron beams by 3D printed polymer samples. 3D printing provides a fast and accurate way to produce custom-shaped samples specific to particular clinical cases.…”

Section: Introductionmentioning

confidence: 99%

Theoretical study of the dose measurements reliability with longitudinally arranged dosimetry films in materials with different densities

et al. 2020

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Investigation purpose. Theoretical study of the depth dose measurements for therapeutic electron beam with longitudinally arranged dosimetry films in materials with different densities. Materials and methods. The work studies how the density of the medium, in which electrons propagate, affects the measured percentage depth dose and its reliability (PDD). For that, we calculate the distribution of the electron beam dose distribution in homogeneous materials with different densities and in a dosimetry film placed in materials with these densities. The density of material in the calculation varies from 0.4 to 2.3 g/cm 3 with a 0.1 g/cm 3 step. The coincidence of the PDD within the experimental measurement accuracy, that equals 4% for dosimetry film and 2% for measurements without it, is chosen as the data fitting criterion. Results. The PDD calculated for two geometries and for different media densities is the result of this work. The calculation shows that PDD difference is negligible when the density of the film is equal to the media one. With decreasing of the media density the difference appears in the regions of both shallow and great depth. The PDD is lower for the geometry with film than for geometry without it in case of these densities. When the media density is rising the opposite effect is observed: the PDD in the film is higher than in geometry without film. The maximum range and therapeutic range in both geometries coincide for the calculated curves throughout the range under study. Discussion. The work shows applicability of the investigated method for measurement of the electron beam percentage depth dose in media 1Corresponding author.

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Utilization of a 3D printer to fabricate boluses used for electron therapy of skin lesions of the eye canthi

Cited by 50 publications

References 28 publications

Additive manufacturing in radiation oncology: a review of clinical practice, emerging trends and research opportunities

Additive manufacturing in radiation oncology: a review of clinical practice, emerging trends and research opportunities

Numerical simulation of electron beam depth dose distribution in water phantom passed through modified plastic materials

Theoretical study of the dose measurements reliability with longitudinally arranged dosimetry films in materials with different densities

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