P aravalvular leakage (PVL) is uncommon but potentially serious complication after valve replacement, which occurs 7% to 17% after mitral valve replacement (MVR) and 2% to 10% after aortic valve replacement.1,2 Although most PVLs are asymptomatic and have a benign clinical course, an estimated 1% to 5% of patients with PVLs show serious clinical consequences, with especially more undesirable outcomes being observed in mitral PVL with higher reoperation rates.
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See Editorial by Khalique and Hahn See Clinical PerspectiveCurrently, transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) are commonly used to evaluate the prosthetic valve along with the presence of PVL. TTE is the first-line imaging method for PVL detection, and TEE can be of additional diagnostic value especially for valves in the mitral position.6,7 However, echocardiography has limitations in prosthetic valve evaluation because of imaging distortions from acoustic shadowing, and TEE is semiinvasive, another limitation.Cardiac computed tomography (CT) is an emerging technique which has received attention for its role in the evaluation of prosthetic valves. A few studies have reported on the use of cardiac CT in the diagnosis of prosthetic valve dysfunction.
8-11Although cardiac CT is thought to have diagnostic value in the detection or localization of PVL 12-14 and thought to help the successful percutaneous closure of mitral PVL, 15 the diagnostic performance of cardiac CT for detection of mitral PVL has not been investigated in a large population.The purposes of our study was to investigate the diagnostic accuracy of cardiac CT for the detection of PVL in prosthetic mitral valves (MVs), using surgical findings as the standard Background-The diagnostic performance of cardiac computed tomography (CT) for detection of paravalvular leakage (PVL) after mitral valve replacement has not been investigated in a large population. We aimed to investigate the diagnostic accuracy of CT for diagnosis of mitral PVL using surgical findings as the standard reference and to compare the diagnostic performance of CT with those of transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE). Methods and Results-A total of 204 patients with previous mitral valve replacement who underwent cardiac CT were retrospectively included. The presence of mitral PVL was analyzed on CT, TTE, and TEE. In 78 patients who underwent redo-surgery, diagnostic performance for the detection of PVL for CT, TTE, and TEE were compared with surgical findings as the standard reference.