Utility of acute phase proteins as biomarkers of transport stress in ewes and beef cattle

Fazio, Francesco; Ferrantelli, Vincenzo; Cicero, Antonello; Casella, Stefania; Piccione, Giuseppe

doi:10.4081/ijfs.2015.4210

Cited by 7 publications

(5 citation statements)

References 21 publications

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“…Our study found that SAA and AGP reactions were elicited by both sea and road transport. Similarly, elevated serum levels of SAA and haptoglobin (Hp) have been recorded 48 h following road transport in ewes [51,52] and beef cattle [52]. Similarly, a single session of inescapable tail shock elevated serum AGP and Hp 24 h later in rats [44].…”

Section: Discussionmentioning

confidence: 99%

The Effects of Sea and Road Transport on Physiological and Electroencephalographic Responses in Brahman Crossbred Heifers

Zulkifli

Abubakar

Sazili

et al. 2019

Animals

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The objective of the current study was to evaluate the effects of sea and road transport on the acute phase proteins (APP), cortisol, metabolic, haematological and electroencephalographic (EEG) responses of Brahman crossbred heifers. Sixty Brahman crossbred heifers were subjected to 14 d of transportation by sea from Darwin Port, Australia, to Pasir Gudang Port, Johor, Malaysia, and 330 km of road transportation. Results revealed that the intensity of response for most blood biochemical parameters increased significantly and were different from the baseline values taken while the animals were in Darwin Port, Australia. Haematological results obtained also revealed a significant increase and were different from the baseline values. Cortisol and APP (bovine alpha 1-acid glycoprotein and serum amyloid-A) values increased significantly and were different from the baseline values. Haematological parameters, APP, cortisol and EEG data (alpha, beta, delta and theta waves, total power and median frequency) decreased significantly following 4 and 7 days post-transport, suggesting a recovery of the animals from the stressfulness of transport. In conclusion, the current results revealed that the concentrations of biochemical and haematological parameters, cortisol, APP and EEG data were affected by both sea and road transport as evidenced by the significant changes recorded from the parameters above.

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Section: Discussionmentioning

confidence: 99%

The Effects of Sea and Road Transport on Physiological and Electroencephalographic Responses in Brahman Crossbred Heifers

Zulkifli

Abubakar

Sazili

et al. 2019

Animals

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“…Acute-phase proteins, first described as early reactants to infectious diseases and inflammation, are also valuable biomarkers of stress [43]. In humans, fibrinogen responses increase with psychophysiological and chronic work stress [44,45].…”

Section: Table-3mentioning

confidence: 99%

Evaluation of the hematological and clinical biochemical markers of stress in broiler chickens

2020

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Background and Aim: Stress significantly affects health and productivity of animals. There is need for affordable and easy-to-assay markers of physiological stress in broilers. This study evaluated hematological and serum biochemical markers of physiologic stress in broiler chickens. Materials and Methods: Thirty day-old broiler chickens were assigned to three groups of ten broilers each during the 56-day study. Group 1 broilers served as the control and were not exposed to any stressors; Group 2 broilers were stocked at the stress density of 50 kg BW m–2 from day 49 to 56 while Group 3 broilers had their feed withdrawn 36 h before blood collection on day 56. Blood samples were collected on day 49 (pre-stress sample) and day 56 (post-stress sample) from all the birds and subjected to hematological and serum biochemical analysis. Results: The parameters did not vary significantly (p>0.05) pre-stress. Post-stress, there were significant variations in the heterophil, lymphocyte, and eosinophil counts and in the heterophil to lymphocyte ratio across the three groups. The concentrations of the plasma fibrinogen and serum albumins, sodium, and sodium to potassium ratio of the broilers varied significantly across the groups. Conclusion: Heterophil, eosinophil, and lymphocyte counts, the heterophil to lymphocyte ratio, plasma fibrinogen, serum albumin, sodium, and sodium to potassium ratio are significant markers of physiological stress in broilers.

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“…As a consequence, pain, inflammation, and fever are reduced (17,22). Recently, there has been an increasing amount of literature on the effects of acute-phase proteins (APPs) in ruminants undergoing transportation (15,44), infusion of lipopolysaccharide (48), viral spp. infections (e.g.…”

Section: Praca Oryginalnamentioning

confidence: 99%

Effects of selected nonsteroidal anti-inflammatory drugs on acute-phase protein levels after dehorning in Holstein heifers

Erdoğan¹,

Akin²,

Ural³

et al. 2019

Medycyna Weterynaryjna

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The purpose of this study was to evaluate the effects of ketoprofen (KTP), flunixin meglumine (FLM), and meloxicam (MLX) administration on acute-phase proteins after dehorning in Holstein heifers. A total of 21 Holstein heifers were enrolled into three groups of equal size (n=7) and administered ketoprofen, flunixin meglumine, or meloxicam, at doses of 2.2 mg/kg, 1.1 mg/kg, and 1 mg/kg body weight, respectively. Serum amyloid A, haptoglobin, and ceruloplasmin levels were determined before the administration of the three drugs (0 hrs) and at 6, 12, 24, 48, and 96 hours post-administration. The mean values (±SD) obtained revealed no significant alteration in APP levels at 0 hrs in any of the three groups. Time-dependent alterations, however, were significant in all groups. Group-time interactions were significant (P < 0.001) for ceruloplasmin concentrations, whereas results for serum amyloid A and haptoglobin levels were deemed non-significant. Inter-group interaction revealed no significant findings regarding serum amyloid A and ceruloplasmin levels, but haptoglobin levels showed a significant difference between the KTP and FLM groups at 48 hrs. It may therefore be reasonably suggested that KTP, FLM, and MLX could all be administered to effect slight changes in acute phase proteins.

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Utility of acute phase proteins as biomarkers of transport stress in ewes and beef cattle

Cited by 7 publications

References 21 publications

The Effects of Sea and Road Transport on Physiological and Electroencephalographic Responses in Brahman Crossbred Heifers

The Effects of Sea and Road Transport on Physiological and Electroencephalographic Responses in Brahman Crossbred Heifers

Evaluation of the hematological and clinical biochemical markers of stress in broiler chickens

Effects of selected nonsteroidal anti-inflammatory drugs on acute-phase protein levels after dehorning in Holstein heifers

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