Utilisation of Cryolipolysis among Asians: A Review on Efficacy and Safety

Putra, Imam Budi; Jusuf, Nelva Karmila; Dewi, Nani Kumala

doi:10.3889/oamjms.2019.318

Cited by 19 publications

(23 citation statements)

References 31 publications

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“…Cryolipolysis is an effective method for noninvasive local subcutaneous fat reduction with highly selective cold-induced adipocyte apoptosis without harming the surrounding tissues [16,44,45]. Thus, the reshaping effect of Cryolipolysis in addition to the effect of low caloric diet enhanced significant improvements in body mass index, lipid profile, and liver enzymes.…”

Section: Discussionmentioning

confidence: 99%

Systemic Effects of Cryolipolysis in Central Obese Women: A Randomized Controlled Trial

et al. 2020

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Background and Objectives To investigate the adding effect of Cryolipolysis to a low‐calorie diet program on lipid profile, liver enzymes, body mass index, waist‐to‐hip ratio, and volume reduction of subcutaneous fat tissue in central obese women. Study Design/Materials and Methods Sixty central obese women were randomly divided into two equal groups. Women in the control group received prescribed low‐calorie diet regimen only, while women in the study group received three Cryolipolysis sessions plus the same dietary regimen for 3 months. Assessment of women in each group for weight, height to obtain the body mass index, waist‐to‐hip ratio, and abdominal subcutaneous fat thickness as well as evaluation of lipid profile and liver enzymes was done just before starting the treatment procedures and immediately after ending the study duration. Results There were statistically significant improvements of waist‐to‐hip ratio, body mass index, total cholesterol, triglycerides, low‐ and high‐density lipoprotein, as well as liver enzymes in favor of the study group (P < 0.001). Conclusion Women who underwent Cryolipolysis and diet program had better improvement in components of lipid profile and liver enzymes than women who were maintained over diet program alone. Measures to decrease waist circumference, associated with abdominal subcutaneous fat reduction, enhanced the systemic effects of Cryolipolysis. Lasers Surg. Med. © 2020 Wiley Periodicals, Inc.

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Section: Discussionmentioning

confidence: 99%

Systemic Effects of Cryolipolysis in Central Obese Women: A Randomized Controlled Trial

et al. 2020

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“…Putra et al [18] performed a review of the literature regarding cryolipolysis in Asian populations and reported that cryolipolysis has displayed good efficacy and safety in Asian patients, although only a few studies, with relatively few subjects, have been performed on Asian populations. In our study, the authors evaluated the efficacy and safety of cryolipolysis based on results obtained from a sufficient number of Asian patients and demonstrated that cryolipolysis has the same efficacy and safety among Asian patients as Putra et al argued.…”

Section: Discussionmentioning

confidence: 99%

Clinical application of cryolipolysis in Asian patients for subcutaneous fat reduction and body contouring

Oh¹,

Shim

Bae

et al. 2020

Arch Plast Surg

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Background Cryolipolysis, a preferred method for minimally invasive body contouring, involves the noninvasive cooling of adipocytes to induce lipolysis without damaging other tissues. This study aimed to evaluate the safety and efficacy of cryolipolysis for the treatment of excessive fat tissue. Methods Between May 2014 and December 2017, 231 patients with 448 areas of interest were enrolled and their records were retrospectively reviewed. We used five different vacuum applicators, and the best-fitting applicator was used for each area. One cycle of cryolipolysis was applied at a cooling intensity factor of 41.6. The efficacy was evaluated 12 weeks after treatment via review of clinical photographs, the pinch test, and ultrasonographic measurements of fat thickness. The occurrence of any complications was also assessed. ResultsThe volume was reduced in all of the areas to which cryolipolysis was applied. The rate of reduction of the fat layer as measured via the pinch test was 19.2%, and the rate of the decrease in fat layer thickness as measured via ultrasonography was 22.8%. Fat reduction of the upper arm differed significantly from that of the abdomen and flank, but no significant difference was found between sexes. The side effects were limited to erythema, edema, bruising, and numbness at the treatment site and resolved without treatment. Conclusions Cryolipolysis, with new and better-fitting applicators, is safe, fast, and effective for the reduction of excessive fat tissue on the abdomen, back, flank, and extremities. It is a good option for treating excess adipose tissue in Asian patients.

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“…The advent of new technology such as noninvasive body-contouring devices has changed the business of surgical treatments and provided new options for addressing fat reduction. Lipolysis devices such as radiofrequency [ 4 ], cryolipolysis [ 5 – 7 ], ultrasound [ 8 , 9 ], and lasers [ 1 , 3 , 10 – 13 ] are now being used worldwide as alternative procedures to remove fat in unwanted areas with a better safety profile compared with liposuction and other surgical procedures [ 1 – 13 ]. Each device has its own mechanism and efficacy profile [ 4 – 12 ].…”

Section: Discussionmentioning

confidence: 99%

“…The efficacy was comparable to the present study, which also demonstrated reduction at 3 and 6 months post-treatment. Cryolipolysis works by inducing adipocyte apoptosis and inflammatory response using cold temperatures without damaging surrounding areas [ 5 – 7 ], while laser lipolysis generates controlled hyperthermia using a specific wavelength and optimal power in the subcutaneous layer and causes photothermal reaction that destroys adipocytes and stimulates inflammatory response [ 10 , 13 ]. In the study by Decorato et al., hyperthermic laser lipolysis was comparable to cryolipolysis in average fat reduction at 3 and 6 months after treatment [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…With the advancement of technology, many noninvasive treatment modalities have been developed to address fat reduction in several areas of the body, such as monopolar and bipolar radiofrequency (RF) [ 4 ], cryolipolysis [ 5 – 7 ], high-intensity focused ultrasound (HIFU) [ 8 , 9 ], and lasers [ 1 , 3 , 10 – 13 ]. These procedures have quicker postoperative recovery and better patient safety profiles [ 1 , 3 – 13 ].…”

Section: Introductionmentioning

confidence: 99%

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Efficacy of Noninvasive 1060-nm Diode Laser for Medial Knee Fat Reduction

Yan

Wanitphakdeedecha

Evangelista

et al. 2022

Dermatol Ther (Heidelb)

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Introduction Laser lipolysis is a rapidly growing noninvasive body-contouring treatment in Asians. There is increasing demand for leg contouring, especially in areas where unwanted fat deposits are prominent despite diet and exercise. Medial fat knees are one of the esthetic concerns of women today and can be a challenging problem in terms of treatment. There are few noninvasive options to remove fat from these areas. This study aims to evaluate the safety and efficacy of a 1060-nm diode laser for medial knee fat reduction. Methods Nineteen subjects with localized unwanted fat on the medial knees were enrolled into this study. All of them were treated with a single session of 1060-nm diode laser at a power setting of 1.0–1.4 W/cm 2 , depending on patient tolerance. Body weight, knee circumference at 3 cm above the medial epicondyle of the femur, and knee fat thickness measured by ultrasonography were recorded at baseline and 1, 3, and 6 months after treatment. Clinical photographs and ultrasound images were taken before and after treatment. Side effects were documented during follow-up visits. Subjects answered a satisfaction questionnaire at the completion of the study. Results All subjects were female, with mean age of 32.3 ± 5.3 years and body weight of 59.8 ± 11.6 kg. The average power setting was 1.3 ± 0.1 W/cm 2 with pain score of 6.1 ± 1.0. Significant reduction in knee circumferences ( p < 0.001) at 1-, 3-, and 6-month follow-up visits compared with baseline, and knee fat thickness measured by ultrasound in both axial and sagittal plane at 1 and 6 months after treatment ( p = 0.036 and p < 0.001, respectively) were recorded. Side effects were mild and transient, including mild erythema and tenderness. Conclusion The 1060-nm diode laser is effective and safe for knee circumference and medial knee fat layer thickness reduction. Trial registration ClinicalTrials.gov identifier, TCTR20220219002. Retrospectively registered on February 19, 2022.

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Utilisation of Cryolipolysis among Asians: A Review on Efficacy and Safety

Cited by 19 publications

References 31 publications

Systemic Effects of Cryolipolysis in Central Obese Women: A Randomized Controlled Trial

Systemic Effects of Cryolipolysis in Central Obese Women: A Randomized Controlled Trial

Clinical application of cryolipolysis in Asian patients for subcutaneous fat reduction and body contouring

Efficacy of Noninvasive 1060-nm Diode Laser for Medial Knee Fat Reduction

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