Clinical application of cryolipolysis in Asian patients for subcutaneous fat reduction and body contouring

Oh, Chang Hyun; Shim, Jeong Su; Bae, Kwang Il; Chang, Jae Hoon

doi:10.5999/aps.2019.01305

Cited by 15 publications

(17 citation statements)

References 25 publications

(36 reference statements)

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“…The reductions in fat mass were within the range observed in previous studies, which used other outcome measurements. 15,24,25 For the majority of the patients (4 out of 5), changes in fat mass followed the same patterns seen with body weight changes (3 patients showed reductions; 1 patient showed an increase). A positive correlation was observed between the percentage change in body weight and percentage change in fat mass, suggesting that lower fat mass, as a result of localized fat reduction using cryolipolysis, may contribute to overall changes in body weight.…”

Section: Discussionmentioning

confidence: 54%

Dual-energy x-ray absorptiometry for evaluating body composition following cryolipolysis

Costa¹,

Borges²,

Marques³

et al. 2022

JDC

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Objectives: Cryolipolysis provides a nonsurgical treatment option for reducing excess subcutaneous fat. Although widely used, clinical outcomes such as photographs, patient questionnaires, and caliper measurements may be affected by subjectivity and operator- dependency. The current case series study evaluated changes in body composition using dual-energy X-ray absorptiometry (DEXA) in patients who underwent cryolipolysis treatment. Methods: between 2019 and 2020, 5 patients underwent cryolipolysis at a dermatology practice in São Paulo, Brazil. Patients were treated in different body regions using a cryolipolysis medical device (CoolSculpting®; ZELTIQ Aesthetics, Inc., Pleasanton, CA, USA) with the CoolAdvantage™ or CoolAdvantage Plus™ vacuum applicators (ZELTIQ Aesthetics, Inc). Pre- and post-treatment, body weight and abdominal circumference were recorded. Fat and lean mass measurements were also obtained using a total body scanner. Results: five patients (4 females, 1 male; mean age, 34 years) were treated in a total of 8 areas (2 cases in the flank, 3 cases in the abdomen, and 3 cases in the back). Three months post-treatment, body weight was reduced in 3 out of 5 (60.0%) patients, and abdominal circumference was reduced in 2 out of 3 (66.7%) patients. Most patients showed reductions in total fat mass (80.0%) and lean mass (60.0%). The percentage change in body weight was also correlated with the percentage change in total fat mass (R=0.81). Region-specific alterations in fat content were also observed. Conclusions: most patients showed changes in body composition, including lower fat mass (5%-36% reductions) 3 months after cryolipolysis treatment. The results suggest that DEXA can be used to objectively visualize and quantify body composition changes following cryolipolysis treatment.

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Section: Discussionmentioning

confidence: 54%

Dual-energy x-ray absorptiometry for evaluating body composition following cryolipolysis

Costa¹,

Borges²,

Marques³

et al. 2022

JDC

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“…In addition, a previous clinical trial had shown reduction of superficial fat through sonographic devices, photographic appraisal, and caliper measurement [20]. A previous descriptive study of 170 Asian cases reported a 5.3 (1.7) mm (23.2%) reduction in fat thickness by high-resolution ultrasonography after cryolipolysis to the abdomen [21]. In addition, sonographic evaluation of intraabdominal adipose tissue yields a coefficient of variation of 64%; therefore, a previous paper did not recommend ultrasound for the assessment of VAT [22].…”

Section: Discussionmentioning

confidence: 99%

Cryolipolysis-induced abdominal fat change: Split-body trials

2020

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Cryolipolysis has been considered as a noninvasive alternative to surgical procedures for reducing subcutaneous fat without affecting the surrounding tissues. However, no clinical trial has investigated changes in the abdominal fat tissue by 12 weeks after cryolipolysis. Therefore, in this split-body trial, we explored whether a single session of unilateral cryolipolysis could change visceral and subcutaneous adipose tissue over a period of 12 weeks. We compared the cross-sectional areas of the abdominal adipose tissue of 15 subjects (9 women; 38.3 [10.8] years) by computed tomography before and at 12 weeks after a single treatment of cryolipolysis to the left abdomen and used the right abdomen as untreated control. In addition, we measured participants’ waist circumference, percentage of body fat (by bioelectrical impedance analysis) at baseline and at 6- and 12-weeks post-treatment. Single unilateral cryolipolysis tended to reduce the cross-sectional areas of visceral adipose tissue, by 8.4 cm2 (9.9%), the waist circumferences, and the percent body fat, by 2.8 cm2 (0.6%), overall. The cross-sectional area of visceral adipose tissues on the treated side significantly decreased, by 6.8 cm2 (15.6%; P = 0.003), and that of the untreated side tended to decrease by 1.2 cm2 (3.6%). Thus, a single unilateral session of noninvasive selective cryolipolysis can be considered as a safe and effective treatment for reduction of visceral adipose tissue over a period of 12 weeks, which should result in metabolic improvement.

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“…The further studies conducted by several authors evidenced the proposed effectiveness for fat reduction in human subjects. It was found that, in general, cryolipolysis causes a 22% reduction of subcutaneous fat thickness when used on the abdomen or flanks, i.e., the most frequent body parts treated by traditional SAL [42][43][44][45][46][47][48][49]. However, although these body parts' efficacy is relatively high, cryolipolysis solely focuses on the reduction of fat tissue, limiting its application and versatility.…”

Section: Discussionmentioning

confidence: 99%

Non-invasive Alternatives for Liposuction

Duncan¹,

Chilukuri²,

Kent³

et al. 2022

Enhanced Liposuction - New Perspectives and Techniques

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Body dissatisfaction due to an increased amount of subcutaneous fat, muscle laxity and/or skin imperfection poses a great concern for today’s society. Invasive surgical procedures intended for an immediate improvement of body contour such as liposuction were perceived as a means of restoring the optimum body shape. However, the invasive nature of liposuction plus a certain amount of discomfort and downtime leads to increasing popularity in the noninvasive esthetic procedures. This chapter aims to emphasize the use of latest noninvasive technologies as a viable alternative to the liposuction. Three patient cases with different levels of treatment outcomes were reviewed. Patients received treatments either with high-intensity focused electromagnetic field (HIFEM) procedure or a combination of HIFEM and synchronized radiofrequency (RF), optionally followed by the simultaneous therapy by targeted pressure energy (TPE) plus monopolar RF. HIFEM alone resolves muscle laxity, reduces the separation of abdominal muscles and reduces abdominal adipose tissue. When combined with synchronized RF, the effect on muscle and fat tissue is enhanced. Concomitant use of monopolar RF and TPE shows considerable improvements in skin quality, including diminished skin laxity or cellulite. The use of HIFEM, RF and TPE technologies can be a good noninvasive liposuction alternative.

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Clinical application of cryolipolysis in Asian patients for subcutaneous fat reduction and body contouring

Cited by 15 publications

References 25 publications

Dual-energy x-ray absorptiometry for evaluating body composition following cryolipolysis

Dual-energy x-ray absorptiometry for evaluating body composition following cryolipolysis

Cryolipolysis-induced abdominal fat change: Split-body trials

Non-invasive Alternatives for Liposuction

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