Utilidad de la ecografía con contraste en la práctica clínica diaria. Estudio multicéntrico español CEUS

Molina, C.; Fontanilla, Teresa; Rodríguez, J.L. del Cura; Villalón, F. Cruz; González, T. Ripollés; Naveros, B. Baudet; Marcos, M.J. Velasco; Sánchez, C. Garre; Arroyo, R. Huertas; García, L. Hernández; Reyes, S.J. Pitti; Rodríguez, Rafael Gómez; López, Ma.J. Calvo; Genover, A. Maroto; Bustos, G. Álvarez; Zatarain, M. Poch; Meléndez, A. Talegón

doi:10.1016/j.rx.2009.11.005

Cited by 12 publications

(1 citation statement)

References 36 publications

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“…A number of other studies also address specificity and sensitivity of CEUS[ 27 - 30 ]. With regard to cost effectiveness, several published studies have reported significant savings when using CEUS[ 31 - 34 ].…”

Section: Discussionmentioning

confidence: 99%

Contrast-enhanced ultrasonography in the evaluation of incidental focal liver lesions: A cost-effectiveness analysis

Šmajerová¹,

Petrášová²,

Little³

et al. 2016

WJG

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AIMTo determine whether contrast-enhanced ultrasonography (CEUS) as the first-line method is more cost-effective in evaluating incidentally discovered focal liver lesions (FLLs) than is computed tomography (CT) and magnetic resonance imaging (MRI).METHODSBetween 2010 and 2015, our prospective study enrolled 459 patients with incidentally found FLLs. The biological nature of FLLs was assessed by CEUS in all patients. CT or MRI examinations were added in unclear cases. The sensitivity and specificity of CEUS were calculated. The total costs of CEUS examinations and of the added examinations performed in inconclusive cases were calculated. Afterwards, the theoretical expenses for evaluating incidentally discovered FLLs using CT or MRI as the first-line method were calculated. The results were compared.RESULTSThe total cost of the diagnostic process using CEUS for all enrolled patients with FLLs was 75884 USD. When the expenses for additional CT and MRI examinations performed in inconclusive cases were added, the total cost was 90540 US dollar (USD). If all patients had been examined by CT or MR as the first-line method, the costs would have been 78897 USD or 384235 USD, respectively. The difference between the cost of CT and CEUS was 3013 USD (4%) and that between MRI and CEUS was 308352 USD (406.3%). We correctly described 97.06% of benign or malignant lesions, with 96.99% sensitivity and 97.09% specificity. Positive predictive value was 94.16% and negative predictive value was 98.52%. In cases with 4 and more lesions, malignancy is significantly more frequent and inconclusive findings significantly less frequent (P < 0.001).CONCLUSIONWhile the costs of CEUS and CT in evaluating FLLs are comparable, CEUS examination is far more cost-effective in comparison to MRI.

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Section: Discussionmentioning

confidence: 99%

Contrast-enhanced ultrasonography in the evaluation of incidental focal liver lesions: A cost-effectiveness analysis

Šmajerová¹,

Petrášová²,

Little³

et al. 2016

WJG

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Contrast-enhanced ultrasound in abdominal imaging

Nicolau

Ripollés

2011

Abdom Imaging

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The administration of a contrast agent is considered an essential tool to evaluate abdominal diseases using Ultrasound. The most targeted organ is the liver, especially to characterize focal liver lesions and to assess the response to percutaneous treatment. However, the expanding abdominal indications of contrast-enhanced ultrasound make this technique an important tool in the assessment of organ perfusion including the evaluation of ischemic, traumatic, and inflammatory diseases.

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Ultrasonido focalizado de alta intensidad con el dispositivo Focal-One®: impacto sobre el antígeno prostático específico y evaluación de la morbilidad durante la experiencia inicial

Perez-Reggeti

Sánchez-Salas

Sivaraman

et al. 2016

Actas Urológicas Españolas

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Utilidad de la ecografía con contraste en la práctica clínica diaria. Estudio multicéntrico español CEUS

Cited by 12 publications

References 36 publications

Contrast-enhanced ultrasonography in the evaluation of incidental focal liver lesions: A cost-effectiveness analysis

Contrast-enhanced ultrasonography in the evaluation of incidental focal liver lesions: A cost-effectiveness analysis

Contrast-enhanced ultrasound in abdominal imaging

Ultrasonido focalizado de alta intensidad con el dispositivo Focal-One®: impacto sobre el antígeno prostático específico y evaluación de la morbilidad durante la experiencia inicial

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