Contrast-enhanced ultrasound in abdominal imaging

Nicolau, Carlos; Ripollés, Tomás

doi:10.1007/s00261-011-9796-8

Cited by 41 publications

(28 citation statements)

References 127 publications

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“…Since the advent of the contrast enhanced sonography (CEUS) in the early 1980s, many studies have shown the potential of this methodology in different fields of medical imaging [1, 2]. Inspired by successes in imaging the liver, efforts have been made by several researchers to test the utility of this technique in the evaluation of the kidney [3, 4].…”

Section: Introductionmentioning

confidence: 99%

Time-intensity curve analysis of contrast-enhanced ultrasound is unable to differentiate renal dysfunction in the early post-transplant period - a prospective study

Araújo

Suassuna

2018

BMC Nephrol

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BackgroundContrast enhanced ultrasonography (CEUS) assessment of kidney allografts mainly focuses on graft rejection. However, studies on delayed graft function (DGF) without acute rejection are still lacking. The aim of this study was to build a time-intensity curve (TIC) using CEUS in non-immunological DGF to understand the utility of CEUS in early transplantation.MethodsTwenty-eight patients in the short-term postoperative period (<14 days) were divided according to the need for dialysis (early graft function [EGF] and [DGF]) and 37 subjects with longer than 90 days follow-up were divided into creatinine tertiles. Time to peak [TTP] and rising time [RT were compared between groups.ResultsEGF and DGF were similar, except for creatinine. In comparison to the late group, medullary TTP and RT were shorter in the early group as well as the delay regarding contrast arrival in the medulla (in relation to cortex) and reaching the medullary peak (in relation to artery and cortex). In the late group, patients with renal dysfunction showed shorter temporal difference to reach medullary peak in relation to artery and cortex.ConclusionsAlthough it was not possible to differentiate EGF and DGF using TIC, differences between early and late groups point to blood shunting in renal dysfunction.

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Section: Introductionmentioning

confidence: 99%

Time-intensity curve analysis of contrast-enhanced ultrasound is unable to differentiate renal dysfunction in the early post-transplant period - a prospective study

Araújo

Suassuna

2018

BMC Nephrol

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“…Conventional ultrasound (CUS) is a readily available, inexpensive, non-invasive, and non-ionizing imaging modality to detect renal masses, but it has limited use when attempting to differentiate between RCC and renal angiomyolipoma (AML). A safe and accurate imaging modality is needed to differentiate between RCC and AML, and contrastenhanced ultrasound (CEUS) using microbubble-based contrast agents has garnered increasing attention in this regard (4,5).…”

Section: Introductionmentioning

confidence: 99%

The diagnostic value of contrast-enhanced ultrasound in differentiating small renal carcinoma and angiomyolipoma

Chen

Wang

Diao

et al. 2015

BST

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“…The recently developed technique of CEUS has markedly expanded the possibilities for sonographic hemodynamic studies. The technique involves the intravenous administration of minute, gas-filled microbubbles that strongly enhance intravascular flow signals 10–12. Measurement of hepatic vein arrival (transit) times (HVAT or HVTT) using a microbubble agent, such as Levovist (Schering AG, Berlin, Germany), SonoVue (Bracco SpA, Milan, Italy), or Sonazoid (GE Healthcare, Oslo, Norway) has been suggested as an ultrasound-based technique to assess the degree of hepatic fibrosis based on the hypothesis that the arrival time of the injected microbubble would be shortened in cirrhosis due to hemodynamic abnormalities, such as arteriovenous shunting or capillarization of the sinusoid 2,3,11,12…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Accuracy of Hepatic Vein Arrival Time Performed with Contrast-Enhanced Ultrasonography for Cirrhosis: A Systematic Review and Meta-Analysis

2017

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Background/AimsWe identified reports in the literature regarding the diagnostic accuracy of hepatic vein arrival time (HVAT) measured by contrast-enhanced ultrasonography (CEUS) to assess hepatic fibrosis in cirrhosis.MethodsThe Ovid MEDLINE, Embase, and Cochrane databases were searched for all studies published up to 23 July 2015 that evaluated liver status using CEUS and liver biopsy (LB). The QUADAS-II (quality assessment of diagnostic accuracy studies-II) was applied to assess the internal validity of the diagnostic studies. Selected studies were subjected to a meta-analysis with MetaDisc 1.4 and RevMan 5.3.ResultsA total of 12 studies including 844 patients with chronic liver disease met our inclusion criteria. The overall summary sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio of the HVAT measured by CEUS for the detection of cirrhosis compared to LB were 0.83 (95% confidence interval [CI], 0.77 to 0.89), 0.75 (95% CI, 0.69 to 0.79), 3.45 (95% CI, 1.60 to 7.43), and 0.28 (95% CI, 0.10 to 0.74), respectively. The summary diagnostic odds ratio (random effects model) was 15.23 (95% CI, 3.07 to 75.47), the summary receiver operator characteristics area under the curve was 0.74 (standard error [SE]=0.14), and the index Q was 0.69 (SE=0.11).ConclusionsBased on a systematic review, the measurement of HVAT by CEUS exhibited an increased accuracy and correlation for the detection of cirrhosis.

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Contrast-enhanced ultrasound in abdominal imaging

Cited by 41 publications

References 127 publications

Time-intensity curve analysis of contrast-enhanced ultrasound is unable to differentiate renal dysfunction in the early post-transplant period - a prospective study

Time-intensity curve analysis of contrast-enhanced ultrasound is unable to differentiate renal dysfunction in the early post-transplant period - a prospective study

The diagnostic value of contrast-enhanced ultrasound in differentiating small renal carcinoma and angiomyolipoma

Diagnostic Accuracy of Hepatic Vein Arrival Time Performed with Contrast-Enhanced Ultrasonography for Cirrhosis: A Systematic Review and Meta-Analysis

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