“…Why were COX activities reduced in the placental tissue of pre‐eclamptic women? Urinary or serum concentrations of prostaglandin E and prostaglandin F were found to be increased in women with pre‐eclampsia [16]. A partial explanation for the decreased activities of placental COX‐1 and COX‐2 may be that COX activity is inhibited as a feedback response to increased prostaglandin production in the placental bed or other tissues [9].…”
“…Why were COX activities reduced in the placental tissue of pre‐eclamptic women? Urinary or serum concentrations of prostaglandin E and prostaglandin F were found to be increased in women with pre‐eclampsia [16]. A partial explanation for the decreased activities of placental COX‐1 and COX‐2 may be that COX activity is inhibited as a feedback response to increased prostaglandin production in the placental bed or other tissues [9].…”
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