Uterine septum: a guideline

Septate Uterus in a Girl with Rubinstein–Taybi Syndrome

“…An interesting remark is that renal anomalies are considered a typical feature of RSTS, and all children with the syndrome should receive a baseline renal ultrasound [ 4 , 5 ]. When a single septate uterus is diagnosed, urinary malformations are usually absent [ 6 , 7 ], which is consistent with the current report.…”

“…As recommended for daily practice, we classified this reported congenital uterine anomaly using the CUME reference standard (internal indentation depth ≥ 10 mm) as septate uterus, in agreement with experts' opinion from different societies in the field [ 8 ]. The recognition of the septum was also in agreement with the ASRM criteria (indentation depth > 15 mm and indentation angle < 90°) [ 7 ].…”

Recurrent Pregnancy Loss: Investigations and Interventions

“…ASRM's original classification system for congenital uterine anomalies has been modified and adapted and is still the most widely used today [41]. In 2012, ESHRE/ ESGE published a classification system aiming to replace the subjective criteria of ASRM's classification by the absolute morphometric criteria [42].…”

“…The uterine septum is the most common abnormality related to RPL [36] and the only remediable one. Despite the lack of randomized and controlled prospective studies comparing surgery to expectant treatment, limited studies indicate that hysteroscopy septal resection is associated with a reduction in subsequent abortion rates and an improvement in live birth rates in patients with RPL [41]. After hysteroscopic resection of the septum, an interval of at least 2 months should be expected for complete healing of the endometrial cavity before a new pregnancy [41].…”

“…In general, CUA may be associated with renal abnormalities in approximately 11-30% of individuals [41]; for this reason there is a need for urinary tract investigation in these cases.…”