Uterine Rupture in Second-Trimester Misoprostol-Induced Abortion After Cesarean Delivery

Abstract

The risk of uterine rupture among women with a prior cesarean delivery undergoing second-trimester abortion using misoprostol is less than 0.3%. This may be acceptable to both patients and providers.

The combination of mifepristone and misoprostol for the termination of pregnancy

“…The risk of uterine rupture in women who underwent misoprostol-induced abortion in the second trimester who had undergone previous cesarean delivery was found to be 0.28%-0.4% in two systematic reviews [12,13].…”

Safety and efficacy of simultaneous use of Mifepristone and Misoprostol in second trimester termination of pregnancy

“…In a meta-analysis of studies of medical abortion, the overall rate of uterine rupture is 0.08 percent, with a rate of 0.28 percent in women with a previous cesarean section. 6 History of curettage, fetal indication, increasing age and 2-day interval between Mifepristone and misoprostol increase the risk of surgical evacuation in cases of second trimester medical termination of pregnancy. The rate of surgical evacuation was 30.8% in a similar study done by Mentula M et al in 2010.…”

Current abortion practices in India: a review of literature

“…It is a safe procedure, with mortality rates comparable with spontaneous abortion. 69 Introducing medical abortion in countries with high abortion-related mortality is feasible step towards achieving millennium development goal 5. While safe abortion services in any form would save women's lives, medical abortion offers resource-poor countries the tools to achieve this with minimal expenditure.…”