Using the Physician Global Assessment in a Clinical Setting to Measure and Track Patient Outcomes

Pascoe, Vanessa L.; Enamandram, Monica; Corey, Kristen; Cheng, Carol E.; Javorsky, Emilia; Sung, Sarah; Donahue, Kevin; Kimball, Alexa B.

doi:10.1001/jamadermatol.2014.3513

Cited by 64 publications

(58 citation statements)

References 18 publications

(21 reference statements)

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“…Therefore, the use of standardized quality measures that can be applied in a clinical setting and simultaneously provides an objective assessment of the severity is recommended. Scoring systems, such as the Physician Global Assessment (PGA), a 5‐ or 6‐point scoring system used to assess disease severity (0 = clear, 1 = almost clear, 2 = mild, 3 = moderate and 4 = severe), are established. Other well‐known scoring systems are the body surface area and the Dermatology Life Quality Index (DLQI) …”

Section: Treatment Algorithmmentioning

confidence: 99%

Pityriasis rubra pilaris: algorithms for diagnosis and treatment

Roenneberg

Biedermann

2018

Acad Dermatol Venereol

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Pityriasis rubra pilaris (PRP) is a rare inflammatory skin disease that affects men and women of all ages and also children. The clinical appearance of PRP is highly variable, as is the individual prognosis. Therefore, stratifying PRP into six disease subtypes represents a first step to personalized medicine for this rare inflammatory skin disease. The next step should be to associate specific therapeutic strategies with these subtypes of PRP. However, no randomized, controlled trials on the treatment of PRP have been performed. Consequently, the actual treatment algorithm for PRP will be based on clinical experience, small case series and case reports. The majority of published evidence is on type I PRP, whereas the treatment experience for other clinical types of PRP is still sparse and has to be gained. Nevertheless, it is now time to start developing valid algorithms as a basis for the diagnosis and treatment of PRP based on the data available. This review makes use of algorithms developed in psoriasis and atopic eczema and puts together recent insights into the pathogenesis, diagnosis and treatment experience of PRP. The innovative intention of this appraisal is to develop a structured algorithm for PRP treatment that should be further developed going forward.

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Section: Treatment Algorithmmentioning

confidence: 99%

Pityriasis rubra pilaris: algorithms for diagnosis and treatment

Roenneberg

Biedermann

2018

Acad Dermatol Venereol

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“…3 Mechanistically, winter flaring of psoriasis may be caused by the season's cold temperature, darkness, and low humidity, which can increase skin permeability, epidermal thickening, and stimulate inflammatory mediator production. 2 Its summer improvement may be attributed to the sun's known immunomodulatory and bactericidal effects.…”

Section: Seasonal Variation Of Acne and Psoriasis: A 3-year Study Usimentioning

confidence: 99%

“…1,2 Psoriasis lesions can be difficult to conceal because of their wide distribution causing patients to be visibly different from those without skin disease. 3 Despite its prevalence, psoriasis remains poorly understood by the lay public, and experiences of stigmatization can range from others staring, to more blatant events such as being asked to leave public places. 4,5 As a result, feelings of shame and embarrassment are common in those with psoriasis, 3 and the condition can have a profound impact on quality of life, resulting in depression and suicidal ideation in some.…”

Section: Seasonal Variation Of Acne and Psoriasis: A 3-year Study Usimentioning

confidence: 99%

Seasonal variation of acne and psoriasis: A 3-year study using the Physician Global Assessment severity scale

Pascoe

Kimball

2015

Journal of the American Academy of Dermatology

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“…During each patient visit, the attending dermatologist recorded the severity of the condition using the Physician Global Assessment Scale as either 0 (almost clear), 1 (mild), 2 (moderate), 3 (severe) or 4 (very severe) based on the degree of erythema and scaling and the extent of the skin lesions. 8 Patients also self-reported symptoms of itchiness and discomfort using a visual analogue scale on a scale of 0 (no symptoms) to 10 (most severe) during each visit.…”

Section: Methodsmentioning

confidence: 99%

The Role of Combination Calcipotriol plus Betamethasone Dipropionate Gel in the Treatment of Moderate-to-Severe Scalp Seborrhoeic Dermatitis

Yap

2019

Sultan Qaboos Univ Med J

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Objectives: This study aimed to investigate the off-label use of a combination calcipotriol plus betamethasone dipropionate (CBD) gel in the treatment of moderate-to-severe scalp seborrhoeic dermatitis (SSD). Methods: This retrospective study involved 32 patients with SSD who were prescribed CBD gel at the Subang Jaya Medical Centre, Selangor, Malaysia, between January 2016 and December 2017. The Physician Global Assessment Scale was used to assess disease severity. Itching/discomfort was evaluated using a visual analogue scale. Results: The mean age was 35.8 ± 6.9 years. Severe disease was seen in 53.1%. Complete clearance was recorded in 15.6%, 40.6% and 59.4% of patients at weeks two, six and 10, respectively. By week 10, 87.5% had achieved marked improvement. Both mean itching and discomfort scores significantly improved at weeks two, six and 10 (P <0.001). Better outcomes were significantly associated with disease duration and itching intensity and discomfort at presentation (P <0.050). Conclusion: CBD gel should be considered as an option for SSD cases not adequately controlled by prior conventional treatment.Keywords: Seborrheic Dermatitis; Scalp Dermatosis; Betamethasone Dipropionate, Calcipotriol Drug Combination; Off-Label Use; Treatment Effectiveness.

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Using the Physician Global Assessment in a Clinical Setting to Measure and Track Patient Outcomes

Abstract: The PGA can be readily incorporated into practice to track patient acne and psoriasis outcomes over time, representing an opportunity for dermatologists to evaluate performance and validate practice guidelines.

Cited by 64 publications

References 18 publications

Pityriasis rubra pilaris: algorithms for diagnosis and treatment

Pityriasis rubra pilaris: algorithms for diagnosis and treatment

Seasonal variation of acne and psoriasis: A 3-year study using the Physician Global Assessment severity scale

The Role of Combination Calcipotriol plus Betamethasone Dipropionate Gel in the Treatment of Moderate-to-Severe Scalp Seborrhoeic Dermatitis

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