“…The gene probes on the TLDA plate were: OAS1, GATA3, PMAIP1, CTSS, FOS, CSF3R, TGFBR2, TP53, B2M, APOBEC3F, TBP, EXT2, HLA-DRA, GNB5, IL11RA, EPHX2, ACTB, CDKN1B, ASL, ACTR1A, POU6F1, LLGL2, PGK1. Inclusion of the specific gene targets was based upon the following criteria: (a) previous studies demonstrating differential expression among control and multiple autoimmune disease cohorts, (b) protein products possess known inflammatory functions, (c) expression levels change in response to pro-inflammatory stimuli (cytokines), and/or (d) protein products have known roles in cell cycle progression and/or apoptosis 5, 8, 30, 31 . Individual transcript levels were normalized to GAPDH levels and expressed as the log 2 transformed [MS-naive/CTRL group] ratio.…”