Using an integrated approach to link biomarker responses and physiological stress to growth impairment of cadmium-exposed larval topsmelt

Rose, Wendy L.; Nisbet, Roger M.; Green, Peter G.; Norris, Sarah; Fan, Teresa W.‐M.; Smith, Edmund H.; Cherr, Gary N.; Anderson, Susan

doi:10.1016/j.aquatox.2006.09.007

Cited by 43 publications

(23 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This contradicted previous hypotheses that predicted either lower metabolic rates (in response to energy shortage or the rampant hypoxia in sulfidic environments) or higher metabolic rate in sulfidic fish (in response to increased metabolic costs of sulfide detoxification; Riesch et al 2011b). It is important to note, however, that it remains unclear how routine metabolic rates measured in our experimental setup compare with routine metabolic rates in situ because all oxygen consumption measurements were conducted in the absence of H 2 S. In general, the presence of physiochemical stressors and toxicants can increase metabolic rates because coping strategies and detoxification pathways are energetically costly (Penttinen and Kukkonen 1998;Rose et al 2006;McKenzie et al 2007). In metazoans, H 2 S detoxification is primarily linked to the sulfide:quinone oxidoreductase pathway (Griesbeck et al 2000;Shahak and Hauska 2008), which oxidizes sulfide to less-toxic forms of sulfur while consuming energy (Ip et al 2004;Hildebrandt and Grieshaber 2008).…”

Section: Metabolic Rate Variation In Sulfidic Environmentsmentioning

confidence: 99%

“…However, the evolution of increased metabolic rates in extreme environments is typically constrained by a reduced supply of resources required for metabolic expenditure (Waterman 1999(Waterman , 2001. While many studies have investigated immediate metabolic costs of exposure to physicochemical stressors and energy limitation (e.g., Haney and Nordlie 1997;Penttinen and Kukkonen 1998;Rose et al 2006;Wang et al 2006;McKenzie et al 2007;McCue 2010), it remains unclear how metabolic rates and metabolic rate plasticity evolve when populations adapt to diverse environmental stressors. Here, we explicitly tested for differences in body size and routine metabolic rate in the context of resource limitation in extremophile fish.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Reduction of Energetic Demands through Modification of Body Size and Routine Metabolic Rates in Extremophile Fish

Passow¹,

Greenway²,

Arias‐Rodríguez³

et al. 2015

Physiological and Biochemical Zoology

View full text Add to dashboard Cite

Variation in energy availability or maintenance costs in extreme environments can exert selection for efficient energy use, and reductions in organismal energy demand can be achieved in two ways: reducing body mass or metabolic suppression. Whether long-term exposure to extreme environmental conditions drives adaptive shifts in body mass or metabolic rates remains an open question. We studied body size variation and variation in routine metabolic rates in locally adapted populations of extremophile fish (Poecilia mexicana) living in toxic, hydrogen sulfide-rich springs and caves. We quantified size distributions and routine metabolic rates in wild-caught individuals from four habitat types. Compared with ancestral populations in nonsulfidic surface habitats, extremophile populations were characterized by significant reductions in body size. Despite elevated metabolic rates in cave fish, the body size reduction precipitated in significantly reduced energy demands in all extremophile populations. Laboratory experiments on common garden-raised fish indicated that elevated routine metabolic rates in cave fish likely have a genetic basis. The results of this study indicate that adaptation to extreme environments directly impacts energy metabolism, with fish living in cave and sulfide spring environments expending less energy overall during routine metabolism.

show abstract

Section: Metabolic Rate Variation In Sulfidic Environmentsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Reduction of Energetic Demands through Modification of Body Size and Routine Metabolic Rates in Extremophile Fish

Passow¹,

Greenway²,

Arias‐Rodríguez³

et al. 2015

Physiological and Biochemical Zoology

View full text Add to dashboard Cite

show abstract

“…Biomarkers or biological responses of organisms to toxicant exposure have been used for decades to indicate stress in aquatic organisms or the magnitude of environmental pollution [6].…”

mentioning

confidence: 99%

Metallothionein as Potential Biomarker of Cadmium Exposure in Persian Sturgeon (Acipenser persicus)

Shariati

Sari

Mashinchian

et al. 2010

Biol Trace Elem Res

View full text Add to dashboard Cite

Metallothionein (MT) concentration in gills, liver, and kidney tissues of Persian sturgeon (Acipenser persicus) were determined following exposure to sublethal levels of waterborne cadmium (Cd) (50, 400, and 1,000 μg l(-1)) after 1, 2, 4, and 14 days. The increases of MT from background levels were 4.6-, 3-, and 2.8-fold for kidney, liver, and gills, respectively. The results showed that MT level change in the kidney is time and concentration dependent. Also, cortisol measurement revealed elevation at the day 1 of exposure and followed by MT increase in the liver. Cd concentrations in the cytosol of experimental tissues were measured, and the results indicated that Cd levels in the cytosol of liver, kidney, and gills increased 240.71-, 32.05-, and 40.16-fold, respectively, 14 days after exposure to 1,000 μg l(-1) Cd. The accumulation of Cd in cytosol of tissues is in the order of liver > gills > kidney. Pearson correlation coefficients showed that the MT content in kidney is correlated with Cd concentration, the value of which is more than in liver and gills. Thus, kidney can be considered as a tissue indicator in A. persicus for waterborne Cd contamination.

show abstract

“…Livers were surgically removed and processed immediately to measure apoptotic DNA fragmentation for genotoxicity through terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay and histopathological analysis through lipid accumulation and glycogen depletion. Detailed procedures of the TUNEL assay were published in Rose (2005) and Rose et al (2006). Briefly, liver samples were fixed in 10% methanol-free formalin for 48 h. The samples were dehydrated, imbedded in paraffin, and sectioned according to standard protocol at Central Histology Services (Sacramento, CA).…”

Section: Sublethal Responses In Fish Livermentioning

confidence: 99%

Sediment quality assessment in tidal salt marshes in northern California, USA: An evaluation of multiple lines of evidence approach

Hwang

Carr

Cherr

et al. 2013

Science of The Total Environment

Self Cite

View full text Add to dashboard Cite

This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues.Other uses, including reproduction and distribution, or selling or licensing copies, or posting to personal, institutional or third party websites are prohibited. The objective of this study was to evaluate the efficacy of integrating a traditional sediment quality triad approach with selected sublethal chronic indicators in resident species in assessing sediment quality in four salt marshes in northern California, USA. These included the highly contaminated (Stege Marsh) and relatively clean (China Camp) marshes in San Francisco Bay and two reference marshes in Tomales Bay. Toxicity potential of contaminants and benthic macroinvertebrate survey showed significant differences between contaminated and reference marshes. Sublethal responses (e.g., apoptotic DNA fragmentation, lipid accumulation, and glycogen depletion) in livers of longjaw mudsucker (Gillichthys mirabilis) and embryo abnormality in lined shore crab (Pachygrapsus crassipes) also clearly distinguished contaminated and reference marshes, while other responses (e.g., cytochrome P450, metallothionein) did not. This study demonstrates that additional chronic sublethal responses in resident species under field exposure conditions can be readily combined with sediment quality triads for an expanded multiple lines of evidence approach. This confirmatory step may be warranted in environments like salt marshes in which natural variables may affect interpretation of toxicity test data. Qualitative and quantitative integration of the portfolio of responses in resident species and traditional approach can support a more comprehensive and informative sediment quality assessment in salt marshes and possibly other habitat types as well.

show abstract

Using an integrated approach to link biomarker responses and physiological stress to growth impairment of cadmium-exposed larval topsmelt

Cited by 43 publications

References 40 publications

Reduction of Energetic Demands through Modification of Body Size and Routine Metabolic Rates in Extremophile Fish

Reduction of Energetic Demands through Modification of Body Size and Routine Metabolic Rates in Extremophile Fish

Metallothionein as Potential Biomarker of Cadmium Exposure in Persian Sturgeon (Acipenser persicus)

Sediment quality assessment in tidal salt marshes in northern California, USA: An evaluation of multiple lines of evidence approach

Contact Info

Product

Resources

About