“…There is still no established treatment regime for ACH since various treatment modalities (topical and systemic treatments, table 1) showed different individual efficiency. Topical treatments with corticosteroids, tar, dithranol, fluorouracil, calcipotriol and tacrolimus were reported as therapeutic options [3,4,5,6,7,8]. In some refractory ACH patients even systemic therapy with retinoids, corticosteroids or different other immunosuppressing and immunomodulating drugs, colchicine, dapsone, sulphasalazine, retinoids, tetracycline, PUVA, methotrexate, cyclosporin A and infliximab did not always lead to total clearance of clinical symptoms [3,4,5,9,10,11,12,13,14].…”