Usefulness of SYNTAX Score to Select Patients With Left Main Coronary Artery Disease to Be Treated With Coronary Artery Bypass Graft

Capodanno, Davide; Capranzano, Piera; Salvo, M.; Caggegi, Anna; Tomasello, Davide; Cincotta, Glauco; Miano, Marco; Patané, Martina; Tamburino, C; Tolaro, Salvatore; Patané, Leonardo; Calafiore, Antonio M.; Tamburino, Corrado

doi:10.1016/j.jcin.2009.06.003

Cited by 161 publications

(133 citation statements)

References 10 publications

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“…In the same time, the CCTA technique provides the unique opportunity of plaque quan- tification, allowing the determination of plaque volume. LM plaques are usually large volume plaques which rupture and embolise frequently during the percutaneous revascularization procedure, therefore the preoperative assessment of plaque volume by CCTA and characteristics could help to prevent the procedure-related complications [13,14]. In this study we demonstrated that use of CCTA Syntax score may better stratify the patients with significant LM stenosis according to their risk than does the stratification based only on angiography-derived Syntax score.…”

Section: Correlation Between Ca Scoring Determined By Ccta and Syntaxmentioning

confidence: 80%

Incremental value of preprocedural coronary computed tomographic angiography to classical coronary angiography for prediction of PCI complexity in left main stenosis

Benedek¹,

Chițu²,

Kovács³

et al. 2013

WJCD

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Introduction: The aim of our study was to assess the incremental value of Coronary Computed Tomography Angiography (CCTA) added to classical coronary angiography, for complex characterization of coronary lesions and prediction of procedural complexity in patients with significant left main (LM) stenoses. Material and Methods: Thirty-six patients with LM disease were enrolled in the study, and each subject underwent CCTA followed by coronary angiography and percutaneous revascularization.

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Section: Correlation Between Ca Scoring Determined By Ccta and Syntaxmentioning

confidence: 80%

Incremental value of preprocedural coronary computed tomographic angiography to classical coronary angiography for prediction of PCI complexity in left main stenosis

Benedek¹,

Chițu²,

Kovács³

et al. 2013

WJCD

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“…In addition, the SYNTAX score is better validated in guiding the treatment choice of coronary artery bypass graft versus PCI. 11,12 On the other hand, the ACEF score is composed of objectively measured variables, whereas the SYNTAX score assessment involves a subjective evaluation of an angiogram, which may be prone to interobserver variability. 15,16 …”

Section: Discussionmentioning

confidence: 99%

Value of Age, Creatinine, and Ejection Fraction (ACEF Score) in Assessing Risk in Patients Undergoing Percutaneous Coronary Interventions in the ‘All-Comers' LEADERS Trial

Wykrzykowska

Garg

Onuma

et al. 2011

Circ: Cardiovascular Interventions

120

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Background-The age, creatinine, and ejection fraction (ACEF) score (age/left ventricular ejection fractionϩ1 if creatinine Ͼ2.0 mg/dL) has been established as an effective predictor of clinical outcomes in patients undergoing elective coronary artery bypass surgery; however, its utility in "all-comer" patients undergoing percutaneous coronary intervention is yet unexplored. Methods and Results-The ACEF score was calculated for 1208 of the 1707 patients enrolled in the LEADERS trial. Post hoc analysis was performed by stratifying clinical outcomes at the 1-year follow-up according to ACEF score tertiles: ACEF low Յ1.0225, 1.0225Ͻ ACEF mid Յ1.277, and ACEF high Ͼ1.277. At 1-year follow-up, there was a significantly lower number of patients with major adverse cardiac event-free survival in the highest tertile of the ACEF score (ACEF low ϭ92.1%, ACEF mid ϭ89.5%, and ACEF high ϭ86.1%; Pϭ0.0218). Cardiac death was less frequent in ACEF low than in ACEF mid and ACEF high (0.7% vs 2.2% vs 4.5%; hazard ratioϭ2.22, Pϭ0.002) patients. Rates of myocardial infarction were significantly higher in patients with a high ACEF score (6.7% for ACEF high vs 5.2% for ACEF mid and 2.5% for ACEF low ; hazard ratioϭ1.6, Pϭ0.006). Clinically driven target-vessel revascularization also tended to be higher in the ACEF high group, but the difference among the 3 groups did not reach statistical significance. The rate of composite definite, possible, and probable stent thrombosis was also higher in the ACEF high group (ACEF low ϭ1.2%, ACEF mid ϭ3.5%, and ACEF high ϭ6.2%; hazard ratioϭ2.04, PϽ0.001). Conclusions-ACEF score may be a simple way to stratify risk of events in patients treated with percutaneous coronary intervention with respect to mortality and risk of myocardial infarction. Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique identifier: NCT00389220. (Circ Cardiovasc Interv. 2011;4:47-56.)

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“…23 The same group of investigators also reported that PCI resulted in a similar risk of 2-year mortality compared with CABG in patients with a SYNTAX score of ≤34 and in a significantly higher risk in patients with a SYNTAX score of >34 in 819 patients with left main disease undergoing revascularization in 2 Italian centers. 24 In the present study, we made an exploratory analysis for the correlation between the SYNTAX score and clinical outcomes. There was no significant difference between the 2 groups not only in all-cause death or cardiac death, but also in the composite endpoints such as MACCE.…”

Section: Association Of the Syntax Score With Clinical Outcomesmentioning

confidence: 99%

Inter- and Intra-Observer Variability for Assessment of the Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) Score and Association of the SYNTAX Score With Clinical Outcome in Patients Undergoing Unprotected Left Main Stenting in the Real World

Shiomi

Tamura

Niki

et al. 2011

Circ J

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Usefulness of SYNTAX Score to Select Patients With Left Main Coronary Artery Disease to Be Treated With Coronary Artery Bypass Graft

Abstract: A SYNTAX score threshold of 34 may usefully identify a cohort of patients with left main disease who benefit most from surgical revascularization in terms of mortality.

Cited by 161 publications

References 10 publications

Incremental value of preprocedural coronary computed tomographic angiography to classical coronary angiography for prediction of PCI complexity in left main stenosis

Incremental value of preprocedural coronary computed tomographic angiography to classical coronary angiography for prediction of PCI complexity in left main stenosis

Value of Age, Creatinine, and Ejection Fraction (ACEF Score) in Assessing Risk in Patients Undergoing Percutaneous Coronary Interventions in the ‘All-Comers' LEADERS Trial

Inter- and Intra-Observer Variability for Assessment of the Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) Score and Association of the SYNTAX Score With Clinical Outcome in Patients Undergoing Unprotected Left Main Stenting in the Real World

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