Inter- and Intra-Observer Variability for Assessment of the Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) Score and Association of the SYNTAX Score With Clinical Outcome in Patients Undergoing Unprotected Left Main Stenting in the Real World

Combination of angiographic and clinical characteristics for the prediction of clinical outcomes in patients undergoing unprotected left main coronary artery stenting

“…Capodanno et al [9] reported that the prognostic value of the SYNTAX score in predicting MACE-when applied in ULMCA patients-was mainly driven by its association with cardiac mortality rather than the ability to predict the need for repeat revascularization. Conversely, Shiomi et al [25] recently observed that high SYNTAX scores are related to a higher rate of TLR in patients undergoing ULMCA PCI but not to the occurrence of cardiac death, myocardial infarction, or Our study confirmed the association of the SYN-TAX score with the need for repeat revascularization during the first year after ULMCA PCI and further demonstrated an association with myocardial infarction. Recent data from the SYNTAX trial have shown that the MACE rate in ULMCA PCI patients-especially with high SYN-TAX scores-is mainly driven by a higher TLR rate due to the increased complexity of coronary anatomy [16].…”

“…In a subanalysis of each MACE endpoint, the SYNTAX score cut-off value ( [25) was significantly related to TLR (P = 0.005) and myocardial infarction (P = 0.03) but not to cardiac death (P = 0.57) in our patient population. Vice versa, the logistic EuroSCORE cut-off value ([7.5%) was significantly associated with cardiac death (P = 0.001) and myocardial infarction (P = 0.01), but not with the need of TLR during the first year (P = 0.25).…”

Predictive Performance of SYNTAX Score II in Patients With Left Main and Multivessel Coronary Artery Disease

“…The anatomical SS has prognostic relevance only for patients assigned to PCI. 9,19, 22 Despite the fact that the STS score has been widely used for risk stratification in cardiac surgery, 23-25 it was not formally validated as a predictive tool for PCI.…”

Long-term clinical outcomes after sirolimus-eluting stent implantation for unprotected left main coronary artery disease

“…All procedures and medical therapies including the duration of dual antiplatelet therapy (DAPT) were left to the discretion of each attending physician. The detailed of the study design and patients' enrollment in this study have been described previously [21]. Written informed consent on the procedure and follow-up protocol was obtained from all patients before the procedure was performed.…”