2019
DOI: 10.1016/j.ophtha.2019.06.014
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Usefulness of Routine Lyme Screening in Patients with Uveitis

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Cited by 11 publications
(6 citation statements)
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“…Vascular leakage and hyperfluorescent foci were detected in the optic disc and retina with fluorescein angiography. Because the serological diagnosis of Lyme disease is difficult and its symptoms are not specific, it is very difficult to diagnose (5,7,9,10). Indirect enzyme-linked immunosorbent test (ELISA), immunoblot analysis and PCR were examined in the diagnostic study of ocular Lyme borreliosis by Mikkila et al They resulted that immunoblot analysis and PCR should be used in addition to ELISA (5).…”
Section: Discussionmentioning
confidence: 99%
“…Vascular leakage and hyperfluorescent foci were detected in the optic disc and retina with fluorescein angiography. Because the serological diagnosis of Lyme disease is difficult and its symptoms are not specific, it is very difficult to diagnose (5,7,9,10). Indirect enzyme-linked immunosorbent test (ELISA), immunoblot analysis and PCR were examined in the diagnostic study of ocular Lyme borreliosis by Mikkila et al They resulted that immunoblot analysis and PCR should be used in addition to ELISA (5).…”
Section: Discussionmentioning
confidence: 99%
“…Lyme disease has been and continues to be frequently associated with uveitis. However, conclusive cases of Lyme-associated uveitis are vanishingly rare [19]. In contrast, uveitides with probable random positive Lyme antibody titers are more frequent; these could well be crossreactive and nonspecific, thus providing a false positive result.…”
Section: Basic Laboratory Diagnostics For All Patients With Uveitismentioning
confidence: 99%
“…Die Borreliose wurde und wird oft mit einer Uveitis in Verbindung gebracht. Jedoch ist eine definitive borrelienassoziierte Uveitis eine absolute Rarität [19]. Häufiger sind dagegen Uveitiden mit wahrscheinlich zufällig positiven Borrelien-Antikörpertitern anzutreffen, die durchaus auch kreuzreaktiv, unspezifisch und somit falsch positiv sein könnten.…”
Section: Zielgerichtete Anamnese Und Diagnostik Bei Uveitis Targeted ...unclassified
“…The utility of routinely checking Lyme serologies in patients who do not display other symptoms characteristic of Lyme disease is low. 4,5…”
Section: Drs Caroline L Minkus and Debra A Goldstein (Chicago Illinois)mentioning
confidence: 99%
“…The utility of routinely checking Lyme serologies in patients who do not display other symptoms characteristic of Lyme disease is low. 4,5 Other rickettsial diseases could be considered, however, as retinal vasculitis and vascular changes are the most common manifestation of posterior uveitis in rickettsial illness. 6 Again, a fluorescein angiogram would be helpful here to aid in diagnosis.…”
mentioning
confidence: 99%