Usefulness of Non–Anteroseptal Region Left Ventricular Hypertrophy Using Cardiac Magnetic Resonance to Predict Repeat Alcohol Septal Ablation for Refractory Obstructive Hypertrophic Cardiomyopathy

Kitamura, Mitsunobu; Amano, Yasuo; Takayama, Morimasa; Shibuya, Junsuke; Matsuda, Junya; Sangen, Hideto; Nakamura, Shun‐ichi; Takano, Hitoshi; Asai, Kuniya; Kumita, Shin‐ichiro; Shimizu, Wataru

doi:10.1016/j.amjcard.2017.03.248

Cited by 5 publications

(2 citation statements)

References 21 publications

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“…The evaluation of left ventricular function is the most important index in the diagnosis of various cardiovascular diseases and the evaluation of drug treatment effect. It can predict whether patients have heart failure, and it plays an important role in the clinic [ 8 ]. Therefore, it is necessary to establish an ideal left ventricular hypertrophy model and its reversal model, and to explore the characteristics of left ventricular structure and function during the process of left ventricular pressure overload-unloading through effective diagnostic means.…”

Section: Introductionmentioning

confidence: 99%

Treatment of Left Ventricular Circulation Disorder: Application of Echocardiography Information Data Monitoring

Chen¹,

Sun²,

Li³

et al. 2020

JMIR Med Inform

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Background Cardiac hypertrophy induced by pressure overload is one of the important causes of heart failure and sudden cardiac death. At present, there are few studies on the outcome of left ventricular hypertrophy and left ventricular function after complete pressure load removal. Objective This study aims to better simulate the changes of left ventricular structure and function during the process of left ventricular pressure overload and deloading, and to explore the application of echocardiography in it. Methods In this study, healthy male (BALB/C) mice were used as research objects to establish an ascending aorta constriction model, to carry out echocardiographic and hemodynamic examinations, to establish an ascending aorta deconstriction model in mice, and to carry out echocardiographic and hemodynamic examinations. Results Compared with the sham operation group, the left ventricular end-systolic diameter (LVESD), left ventricular end-diastolic diameter (LVEDD), interventricular septal (IVS), and left ventricular posterior wall (LVPW) in the constriction operation group were significantly increased (P=.02, P=.02, P=.02, and P=.02, respectively). LVESD, LVEDD, IVS, and LVPW in the early and late constriction groups were significantly decreased, and the degree of decrease in the early group was greater than that in the late group; compared with the sham operation group, left ventricular diastolic pressure in the constriction operation group increased significantly at 9 and 15 weeks after operation (P=.03). Left ventricular systolic pressure at 15 weeks after operation decreased to a certain extent but was higher than that of the sham operation group (P=.02). The maximal rate of the increase of left ventricular pressure at 3 weeks, 9 weeks, and 15 weeks after operation decreased significantly (P=.03, P=.02, and P=.02, respectively). Conclusions In this study, the ascending aorta coarctation model and descending aorta coarctation model were successfully established, which verifies the value of echocardiography information data monitoring in the treatment of left ventricular circulation disorders and the evaluation of surgical treatment.

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Section: Introductionmentioning

confidence: 99%

Treatment of Left Ventricular Circulation Disorder: Application of Echocardiography Information Data Monitoring

Chen¹,

Sun²,

Li³

et al. 2020

JMIR Med Inform

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“…The location and extent of LGE induced by ASA and non-anteroseptal myocardial hypertrophy are predictive of the success rate of ASA. 60 , 61 Contrast-enhanced cine SSFP can also be used to evaluate the ablated myocardium, including the microvascular obstruction and enhanced region ( Fig. 20 ).…”

Section: Introductionmentioning

confidence: 99%

Cardiac MR Imaging of Hypertrophic Cardiomyopathy: Techniques, Findings, and Clinical Relevance

et al. 2018

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Hypertrophic cardiomyopathy (HCM) is a relatively common myocardial genetic disease having a wide variety of symptoms and prognoses. The most serious complications of HCM are sudden cardiac death induced by ventricular arrhythmia or inappropriate changes in blood pressure, and heart failure. Cardiac MR imaging is a valuable imaging method for detecting HCM because of its accurate measurement of wall thickness and myocardial mass without limited view and the unique ability of late gadolinium enhancement (LGE) to identify myocardial fibrosis related to the prognosis of HCM. Tagging and T1 or T2 mapping MR imaging techniques have emerged as quantitative methods for the evaluation of disease severity. In this review, we introduce the MR imaging techniques applied to HCM and demonstrate the typical phenotypes and some morphological characteristics of HCM. In addition, we discuss the clinical relevance of MR imaging for risk stratification and management of HCM.

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Choice of Septal Reduction Therapies and Alcohol Septal Ablation

Fifer

2019

Cardiology Clinics

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Usefulness of Non–Anteroseptal Region Left Ventricular Hypertrophy Using Cardiac Magnetic Resonance to Predict Repeat Alcohol Septal Ablation for Refractory Obstructive Hypertrophic Cardiomyopathy

Cited by 5 publications

References 21 publications

Treatment of Left Ventricular Circulation Disorder: Application of Echocardiography Information Data Monitoring

Treatment of Left Ventricular Circulation Disorder: Application of Echocardiography Information Data Monitoring

Cardiac MR Imaging of Hypertrophic Cardiomyopathy: Techniques, Findings, and Clinical Relevance

Choice of Septal Reduction Therapies and Alcohol Septal Ablation

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