Usefulness of latent left ventricular dysfunction assessed by Bowditch Treppe to predict stress-induced pulmonary hypertension in minimally symptomatic severe mitral regurgitation secondary to mitral valve prolapse

Negative stress echo: Further prognostic stratification with assessment of pressure–volume relation

“…Several have been the attempts to transfer the forcefrequency relationship from the experimental laboratory to the clinical setting [3,4,7,[18][19][20][21][22][23]. Extensive data demonstrate that the force-frequency relation is profoundly modified in heart failure [8], ischemic [7], dilated [7,20,22] or hypertrophic [21] cardiomyopathy, as well as in hypertensive [18,19] and valvular [23,24] disease.…”

“…Extensive data demonstrate that the force-frequency relation is profoundly modified in heart failure [8], ischemic [7], dilated [7,20,22] or hypertrophic [21] cardiomyopathy, as well as in hypertensive [18,19] and valvular [23,24] disease. Nevertheless up to date prognostic data seem to be lacking.…”

Chronic Mitral Regurgitation: A Pilot Study to Assess Preoperative Left Ventricular Contractile Function Using Speckle-Tracking Echocardiography

“…3 Abnormal preoperative LVEF is a powerful predictor of postoperative LV dysfunction, which carries a poor prognosis, 5,8,11 but its sensitivity to detect early contractile abnormalities is poor. LVEF frequently remains normal despite the presence of significant contractile dysfunction during the compensated phase of chronic MR. Several echocardiographic methods have been proposed to detect latent ventricular dysfunction in patients with chronic severe MR: LV dP/dt, 17 end-systolic wall stress, 18 stress echocardiography (exercise or dobutamine), [19][20][21][22] ultrasound tissue characterization, 23 and DTI. 24,25 However, most of these techniques have limitations that may reduce their applicability in daily clinical practice.…”

Can We Improve Outcomes in Patients With Previous Coronary Artery Bypass Surgery Admitted for Acute Coronary Syndrome?

“…A higher number of patients and a longer follow-up could probably have enhanced the difference and, therefore, allowed us to conclude (as other authors have 10,17,[20][21][22] ) that patients with a history of CABG PCI and MI. This could be explained by adherence to guidelines in our series regarding surgical revascularization, and by the fact that this patient subgroup has a longer history of atherosclerotic disease.…”