Use of wide-spectrum antimicrobials with blood culture tests during chemotherapy as an accurate marker of febrile neutropenia in the DPC database: A validation study

Matsuda, Kensuke; Ise, Masataka; Shimura, Arika; Honda, Akira; Masamoto, Yosuke; Jo, Taisuke; Yasunaga, Hideo; Kurokawa, Mineo

doi:10.1016/j.jiac.2021.07.012

Cited by 3 publications

(8 citation statements)

References 5 publications

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“…Our definition of FN may have included a certain number of patients without neutropenia because neutrophil counts were not included in the database. However, our validation study showed that the definition used in this study had a positive predictive value of 80% 8 …”

Section: Characteristics Patients Aged ≥80 Years N = 1819mentioning

confidence: 68%

“…The antibiotics used to define FN were limited to cefepime, piperacillin‐tazobactam and meropenem because these are the only antibiotics approved for FN treatment in Japan. Our previous validation study indicated that this definition was generally accurate for identification of FN patients 8 …”

Section: Characteristics Patients Aged ≥80 Years N = 1819mentioning

confidence: 98%

“…Our previous validation study indicated that this definition was generally accurate for identification of FN patients. 8 To exclude non-primary prophylactic use of antimicrobials and G-CSF, patients with active bacterial infections at admission were excluded from the study. Onset of FN was defined as the day of performance of a blood culture test.…”

Section: Risk Of Febrile Neutropenia In Very Elderly Patients Aged ≥8...mentioning

confidence: 99%

“…However, our validation study showed that the definition used in this study had a positive predictive value of 80%. 8 Thus, we consider that patients who developed FN were identified appropriately. Second, the study only evaluated the incidence of FN in the first cycle of R-CHOP.…”

Section: Risk Of Febrile Neutropenia In Very Elderly Patients Aged ≥8...mentioning

confidence: 99%

“…3 The CIS-fatigue (subscale; 8 items) and the shortened CIS (4 items) can be used independently and have a cut-off for severe fatigue, which may identify patients who could benefit from an intervention. [7][8][9] Although diseasespecific quality-of-life tools may be more appropriate to evaluate the general effect of ITP treatment, the CIS respects patients' own emphasis on fatigue and is better suited to evaluate fatigue-targeted interventions.…”

Section: Su Pp Ort I Ng I N For M At Ionmentioning

confidence: 99%

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Risk of febrile neutropenia in very elderly patients aged ≥80 years receiving their first cycle of R‐CHOP regimen: a nationwide real‐world study in Japan

Matsuda¹,

Jo²,

Shimura³

et al. 2022

Br J Haematol

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Section: Characteristics Patients Aged ≥80 Years N = 1819mentioning

confidence: 68%

Section: Characteristics Patients Aged ≥80 Years N = 1819mentioning

confidence: 98%

Section: Risk Of Febrile Neutropenia In Very Elderly Patients Aged ≥8...mentioning

confidence: 99%

Section: Risk Of Febrile Neutropenia In Very Elderly Patients Aged ≥8...mentioning

confidence: 99%

Section: Su Pp Ort I Ng I N For M At Ionmentioning

confidence: 99%

See 3 more Smart Citations

Risk of febrile neutropenia in very elderly patients aged ≥80 years receiving their first cycle of R‐CHOP regimen: a nationwide real‐world study in Japan

Matsuda¹,

Jo²,

Shimura³

et al. 2022

Br J Haematol

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Validation studies of Japanese administrative health care data: A scoping review

Yamana

Konishi

Yasunaga

2023

Pharmacoepidemiology and Drug

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Purpose Large‐scale administrative health care databases are increasingly being utilized for research. However, there has not been much literature that validated administrative data in Japan; a previous review identified six validation studies published between 2011 and 2017. We conducted a literature review of studies that assessed the validity of Japanese administrative health care data. Methods We searched for studies published by March 2022 that compared individual‐level administrative data with a reference standard from another data source, as well as studies that validated administrative data using other data within the same database. The eligible studies were also summarized based on characteristics which included data types, settings, reference standard used, numbers of patients, and conditions validated. Results There were 36 eligible studies, including 29 that used external reference standard and seven that validated administrative data using other data within the same database. Chart review was the reference standard in 21 studies (range of the numbers of patients, 72–1674; 11 studies conducted in single institutions and nine studies in 2–5 institutions). Five studies used a disease registry as the reference standard. Diagnoses of cardiovascular diseases, cancer, and diabetes were frequently evaluated. Conclusions Validation studies are being conducted at an increasing rate in Japan, although most of them are small scale. Further large‐scale comprehensive validation studies are necessary to effectively utilize the databases for research.

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Validity of diagnoses of respiratory diseases recorded in a Japanese administrative database

Awano

Urushiyama

Yamana

et al. 2023

Respiratory Investigation

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Use of wide-spectrum antimicrobials with blood culture tests during chemotherapy as an accurate marker of febrile neutropenia in the DPC database: A validation study

Cited by 3 publications

References 5 publications

Risk of febrile neutropenia in very elderly patients aged ≥80 years receiving their first cycle of R‐CHOP regimen: a nationwide real‐world study in Japan

Risk of febrile neutropenia in very elderly patients aged ≥80 years receiving their first cycle of R‐CHOP regimen: a nationwide real‐world study in Japan

Validation studies of Japanese administrative health care data: A scoping review

Validity of diagnoses of respiratory diseases recorded in a Japanese administrative database

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