Use of TIE techniques to characterize industrial effluents in the Pearl River Delta region

Fang, Yi-Xiang; Ying, Guang‐Guo; Zhang, Lijuan; Zhao, Jian‐Liang; Su, Haijun; Yang, Bin; Liu, Shan

doi:10.1016/j.ecoenv.2011.10.003

Cited by 35 publications

(28 citation statements)

References 39 publications

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“…The cartridges were forced under vacuum at a flow rate of approximately 6 mL/min. After extraction, 200 mL elutriate residual was also collected for bioassay by the modified method [20]. Silica sand was used as procedure blanks.…”

Section: Sediment Elutriate Preparationmentioning

confidence: 99%

Thyroid hormone disrupting activities of sediment from the Guanting Reservoir, Beijing, China

Ren

et al. 2014

Journal of Hazardous Materials

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h i g h l i g h t s• Yeast bioassays were used to evaluate the TR disrupting activities of the sediments.• The organic extracts showed TR antagonistic activities.• The elutriates also significantly antagonized the TR.• The causes of toxicity in the elutriates appear to be partly related to the heavy metals. a r t i c l e i n f o a b s t r a c tIn the present study, yeast bioassays were used to evaluate and characterize the thyroid receptor (TR) disrupting activities of the organic extracts and elutriates of the sediments from the Guanting Reservoir, Beijing, China. An accelerated solvent extraction was used to separate the organic extracts, which were subjected to a yeast bioassay. The organic extracts could affect thyroid hormone signaling by decreasing the binding of the thyroid hormone. The TR antagonistic activity equivalents (TEQ bio ) referring to amiodarone hydrochloride were calculated and the observed TEQ bio-organic extracts ranged from 25.4 ± 3.7 to 176.9 ± 18.0 g/g. Elutriate toxicity tests using the modified yeast bioassay revealed that the elutriates also significantly antagonized the TR, with the TEQ bio-elutriates ranging from N.D. to 7.8 ± 0.8 g/L. To characterize the toxic compounds, elutriates were extracted by using a C18 cartridge or treated with ethylenediaminetetraacetic acid (EDTA, 30 mg/L). The results suggested that the addition of EDTA eliminated over 74.3% of the total effects, and the chemical analysis revealed that heavy metals, some of which exhibited TR disrupting potency, for example Zn and Cd, were detectable with higher concentrations in the elutriates. Thus, the cause(s) of toxicity in the elutriate appear to be partly related to the heavy metals.

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Section: Sediment Elutriate Preparationmentioning

confidence: 99%

Thyroid hormone disrupting activities of sediment from the Guanting Reservoir, Beijing, China

Ren

et al. 2014

Journal of Hazardous Materials

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“…When the application of multiple biossays aimed to evaluate distinct bioactivities, the tests were mostly performed in parallel. For instance, bioassay batteries evaluated the occurrence of different toxicity mechanisms [50,51] or effects on different trophic levels in the two TIE studies [32,33]. When instead the aim of multiple methods was to analyse different aspects of the same bioactivity or toxicity mechanism, there was the prevalence of tiered approach biotesting [19,39,45].…”

Section: Biotesting Strategymentioning

confidence: 99%

“…Zebrafish up to 5 days post fertilization (dpf ) were the life stages mostly applied, except for experiments that extended the assays up to 6 to 7 dpf [34,49,53,56,57] or a few studies with adults [33,47,59]. Environmental toxicology studies for the most part performed exposure not only in 24-well plates (200 μL to 2 mL per embryo or larva) but also in crystallization dishes, scintillation vials or beakers (450 μL to 5 mL per embryo or larva, 40 to 300 mL per adult), while natural product studies were performed exclusively in multiwell-plate setup (<100 to 250 μL per embryo or larva).…”

Section: Prevalent Life Stages and Exposure Setupsmentioning

confidence: 99%

“…Review papers, or studies that did not include the EDA procedure or zebrafish bioassays, were excluded. Two studies that followed procedures for toxicity identification evaluation (TIE) [32,33] instead of EDA were included since the similarities between both approaches [5] make them relevant for this review. In total, 29 publications were found (Table 1), which were carefully evaluated for research area, objective, investigated matrix, bioassay endpoint and setup, biotesting strategy, and study outcomes.…”

Section: Eda Studies Integrating Zebrafish Bioassaysmentioning

confidence: 99%

“…Natural product studies aimed to identify bioactive compounds for pharmacological applications, investigating mostly plant extracts [19,[34][35][36][37][38][39][40][41][42][43][44][45] but also extracts of bacteria [46], cyanobacteria and algae [47], seaweed [48] and marine organisms [49]. Environmental toxicology studies aimed to identify the toxic compounds in various environmental samples, including marine and fluvial sediments [50][51][52], soil [53], cyanobacteria and algae [54,55], industrial effluent [33], rubber tyre leachates [32], oil sand process waters [56,57] and river pore water [58]. Finally, fish skin extracts were investigated in a behavioural sciences study [59].…”

Section: Research Areas and Investigated Matricesmentioning

confidence: 99%

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The value of zebrafish as an integrative model in effect-directed analysis - a review

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Multispecies acute toxicity evaluation of wastewaters from different treatment stages in a coking wastewater‐treatment plant

Zhao

Jiang

Yan

et al. 2014

Enviro Toxic and Chemistry

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Coking wastewater contributes approximately 5% of the total discharge volume of industrial wastewaters every year in China. The toxicity of coking wastewater to aquatic organisms is still unknown. The authors evaluated the toxicity of wastewater from different treatment stages in a coking wastewater treatment plant, South China, using 5 test species belonging to different trophic levels: luminous bacteria, green alga, a crustacean, duckweed, and zebrafish embryos. The raw influent displayed the highest toxicity to the test species, with toxic units ranging from 16.2 to 1176. The toxicity in the wastewater was then gradually removed by sequential primary treatment, biological fluidized-bed treatment, and secondary clarifier treatment. The toxic unit of the final effluent was reduced to 2.26 for the green alga (Pseudokirchneriella subcapitata) and to 0 for the other 4 organisms. Quantitative analysis of metals and polycyclic aromatic hydrocarbons (PAHs) and qualitative scanning by gas chromatography-mass spectrometry showed the presence of a variety of pollutants in the coking wastewaters. Multivariate statistical analysis revealed that the toxicity in the coking wastewater was correlated to the chemical oxygen demand, total nitrogen, ammonia nitrogen, volatile phenols, sulfide, metals (Cr, As, Sb, Hg, Pb, and Ni), and SPAHs. Based on the results, it is required to set a safety emission limit value for the discharge of coking wastewater to protect aquatic organisms in the receiving water bodies.

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Use of TIE techniques to characterize industrial effluents in the Pearl River Delta region

Cited by 35 publications

References 39 publications

Thyroid hormone disrupting activities of sediment from the Guanting Reservoir, Beijing, China

Thyroid hormone disrupting activities of sediment from the Guanting Reservoir, Beijing, China

The value of zebrafish as an integrative model in effect-directed analysis - a review

Multispecies acute toxicity evaluation of wastewaters from different treatment stages in a coking wastewater‐treatment plant

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