Use of Sulfanilamide After Transurethral Prostatectomy

Randomized prospective comparison of fosfomycin and cefotiam for prevention of postoperative infection following urological surgery

“…No difference was observed between I FOM 56 4 0 3 1 0 CTM 59 3 0 1 0 2 II FOM 39 5 0 4 1 0 CTM 41 6 2 2 1 1 II-1 FOM 7 0 0 0 0 0 CTM 13 2 1 0 1 0 II-2 FOM 29 3 0 2 1 0 CTM 25 1 0 0 0 1 II-3 FOM 3 2 0 2 0 0 CTM 3 3 1 2 0 0 the overall clinical effi cacy of FOM and CTM. Past studies of drugs used to prevent infection after urologic surgery often focused solely on transurethral prostate surgery [11][12][13] and less frequently examined factors associated with open surgery. 14 Two reports published in Japan dealt with prospective evaluation of the incidence of infection after urologic open surgery, using penicillins or cephems as prophylactic antibiotics, but they did not specify the drug.…”

“…16,17 Several studies have compared the rate of postoperative infection in patients who received antibiotic prophylaxis after transurethral surgery to the rate in patients who received no antibiotic prophylaxis. 13,18 The incidence of infection in patients not given prophylactic antibiotic therapy was high (bacteremia, 10%-32%; urinary tract infection, 16%-70%). 19 Additionally, in a study of patients undergoing radical nephrectomy, 20 the overall postoperative infection rate was 27.3% in the group not given prophylactic antibiotic therapy, compared to 7.7% in the group given such therapy.…”

Concentrations of ceftriaxone (1,000 milligrams intravenously) in abdominal tissues during open prostatectomy

“…The open resection of the prostate is a commonplace operation in older men, and urinary tract infections and other infectious complications are major causes of morbidity. Antibacterial prophylaxis has been available to urologic surgeons for more than 50 years (10). Broad-spectrum cephalosporins and penicillins are most frequently used, and the use of fluoroquinolones has also been evaluated (2).…”