Use of strain and tissue velocity imaging for early detection of regional myocardial dysfunction in patients with beta thalassemia

Abstract

Thalassemia patients have regional systolic dysfunction in the lateral LV wall and regional diastolic dysfunction in the septal and RV wall. TVI and the newer modality SI are promising tools for quantitative assessment of regional myocardial function. SI seems more capable of early detection of regional myocardial dysfunction.

The efficacy of tissue Doppler imaging in predicting myocardial iron load in patients with beta-thalassemia major: correlation with T2* cardiovascular magnetic resonance

“…Tissue Doppler imaging can detect regional systolic and diastolic myocardial dysfunction earlier than global dysfunction in thalassemia patients [8][9][10][11][12][13]. Our results were in accordance with previous studies; [8].…”

“…Therefore, T2* MR is still unsuitable for screening of patients with TM. Previous studies have reported that tissue Doppler imaging (TDI) can detect early myocardial dysfunction related to iron overload [8][9][10][11][12][13].…”

Prediction of Short-Term Outcomes in Patients With Idiopathic Dilated Cardiomyopathy Referred for Transplantation Using Standard Echocardiography and Strain Imaging

“…Numerous studies have elucidated the utility of strain rate imaging in the detection of myocardial diseases even in their subclinical stages, also as myocardial involvement in non-cardiac diseases, such as amyloidosis, diabetic heart disease, beta-thalassemia, Friedriech ataxia and others (74)(75)(76)(77)(78). It is also helpful in distinguishing between hypertrophic cardiomyopathy, athelete's heart and hypertrophy caused by hypertension (79,80).…”

Ecocardiografia de pacientes talassêmicos sem insuficiência cardíaca em tratamento com transfusões sanguíneas e quelação

“…Some reports indicate Doppler-echocardiogram with tissue Doppler as a promising technique for this situation [12][13][14][15][16][17][18][19] . However, data obtained by this method are still scarce, particularly in relation to left ventricular diastolic function and right ventricular structure and function.…”