Use of pretreatment prostate specific antigen doubling time to predict outcome after radical prostatectomy

Abstract

To better understand the implications of the rate of prostate speci®c antigen (PSA) changes in prostate carcinoma. MethodWe retrospectively calculated PSA doubling times prior to surgery in 63 patients with prostate carcinoma. The calculated values were compared with ®nal pathologic ®ndings and with rates of PSA failure after surgery.