Use of Platelet-Rich Plasma With Split-Thickness Skin Grafts in the High-Risk Patient

Schade, Valerie L.; Roukis, Thomas S.

doi:10.1177/1938640008317782

Cited by 28 publications

(23 citation statements)

References 19 publications

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“…There was no difference found in graft viability between two groups but group II wounds showed early primary healing than group I. Schade and Roukis (2008) reported that, the addition of Platelet Rich Plasma to split thickness skin grafts recipient sites seems to enhance primary healing and reduce healing time, likely as a result of shearing force reduction and enhancement of the wound environment with growth factors.…”

Section: Resultsmentioning

confidence: 87%

A comparative clinical study of partial thickness mesh skin grafts with and without addition of platelet rich plasma in dogs

Preethi

Kumar

Raghavender

et al. 2017

IJAR

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The objective of this study was to reconstruct the skin defects with partial thickness mesh skin grafts and to compare the efficacy of platelet rich plasma along with skin grafting. The present study was performed on ten dogs with twelve wounds which were unamenable to primary closure. All the wounds were reconstructed with partial thickness mesh skin grafting technique in which six wounds were assigned to group-I and remaining were similarly reconstructed followed by injection of platelet rich plasma were assigned to group-II. It was concluded from the present study that, partial thickness mesh skin grafting procedure showed good results for correction of skin defects. The group II wounds showed early primary healing with no difference in graft viability.

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Section: Resultsmentioning

confidence: 87%

A comparative clinical study of partial thickness mesh skin grafts with and without addition of platelet rich plasma in dogs

Preethi

Kumar

Raghavender

et al. 2017

IJAR

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“…Three articles used bioengineered or advanced techniques (platelet-rich plasma) in conjunction with STSG [18–20]. Three articles applied STSG over a (gracilis muscle) free flap or subcutaneous flap [21–23].…”

Section: Resultsmentioning

confidence: 99%

The Use of Split-Thickness Skin Grafts on Diabetic Foot Ulcerations: A Literature Review

McCartan

Dinh

2012

Plastic Surgery International

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Diabetic foot ulcerations are historically difficult to treat despite advanced therapeutic modalities. There are numerous modalities described in the literature ranging from noninvasive topical wound care to more invasive surgical procedures such as primary closure, skin flaps, and skin grafting. While skin grafting provides faster time to closure with a single treatment compared to traditional topical wound treatments, the potential risks of donor site morbidity and poor wound healing unique to the diabetic state have been cited as a contraindication to its widespread use. In order to garner clarity on this issue, a literature review was undertaken on the use of split-thickness skin grafts on diabetic foot ulcers. Search of electronic databases yielded four studies that reported split-thickness skin grafts as definitive means of closure. In addition, several other studies employed split-thickness skin grafts as an adjunct to a treatment that was only partially successful or used to fill in the donor site of another plastic surgery technique. When used as the primary closure on optimized diabetic foot ulcerations, split-thickness skin grafts are 78% successful at closing 90% of the wound by eight weeks.

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“…Method of healing time measurement was not explained in this study. Only co-morbidities were considered in this study but not the duration of diabetes [17][18][19].…”

Section: Resultsmentioning

confidence: 99%

Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management

Maramreddy¹

2016

IJARS

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Introduction: Split skin grafting is widely used surgical procedure for the treatment of ulcers. Graft survival depends on number of factors like vascularity, wound infection etc. diabetes is associated with endothelial dysfunction, neuropathy, wound infection which collectively affect the graft survival. Aim:To compare the amount of graft uptake, the post operative complications and survival of split thickness skin graft in diabetic and non diabetic wound management. Materials and Methods:In our prospective nonrandomized comparative study total 104 patients with ulcer were included of which 52 were diabetic and 52 were non-diabetic. All of them underwent split skin grafting as part of their wound management. Comparison was made between two groups in terms of amount of graft uptake, post operative wound infection, re-ulceration, revisional surgery, donor site infection.

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Use of Platelet-Rich Plasma With Split-Thickness Skin Grafts in the High-Risk Patient

Cited by 28 publications

References 19 publications

A comparative clinical study of partial thickness mesh skin grafts with and without addition of platelet rich plasma in dogs

A comparative clinical study of partial thickness mesh skin grafts with and without addition of platelet rich plasma in dogs

The Use of Split-Thickness Skin Grafts on Diabetic Foot Ulcerations: A Literature Review

Survival of Split Thickness Skin Graft in Diabetic and Non-diabetic Wound Management

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