Use of plant-derived antimicrobials for improving the safety of poultry products

Venkitanarayanan, Kumar; Johny, Anup Kollanoor; Darre, M. J.; Donoghue, Ann M.; Donoghue, Dan

doi:10.3382/ps.2012-02764

Cited by 50 publications

(34 citation statements)

References 92 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The compounds showing the strongest antimicrobial action against both bacteria were eugenol (MIC = 100 μg ml −1 ) and thymol (MIC = 200 μg ml −1 ). These results indicate that these natural generally recognised as safe (GRAS) terpenoids, traditionally used as dietary constituents (Gyawali & Ibrahim 2012;Venkitanarayanan et al 2013), possess strong antimicrobial properties and can be used at low concentrations as a natural alternative or complementary strategy for preventing S. aureus and S. epidermidis proliferation. Moreover, this antiStaphylococcus activity opens the possibility of using eugenol and thymol in the prevention and treatment of skin infections and other opportunistic nosocomial pathologies caused by S. aureus or S. epidermidis without concerns about toxicity.…”

Section: Antimicrobial Activity Of Non-toxic Plant-derived Compoundsmentioning

confidence: 94%

Non-toxic plant metabolites regulateStaphylococcusviability and biofilm formation: a natural therapeutic strategy useful in the treatment and prevention of skin infections

et al. 2014

View full text Add to dashboard Cite

In the present study, the efficacy of generally recognised as safe (GRAS) antimicrobial plant metabolites in regulating the growth of Staphylococcus aureus and S. epidermidis was investigated. Thymol, carvacrol and eugenol showed the strongest antibacterial action against these microorganisms, at a subinhibitory concentration (SIC) of ≤ 50 μg ml(-1). Genistein, hydroquinone and resveratrol showed antimicrobial effects but with a wide concentration range (SIC = 50-1,000 μg ml(-1)), while catechin, gallic acid, protocatechuic acid, p-hydroxybenzoic acid and cranberry extract were the most biologically compatible molecules (SIC ≥ 1000 μg ml(-1)). Genistein, protocatechuic acid, cranberry extract, p-hydroxybenzoic acid and resveratrol also showed anti-biofilm activity against S. aureus, but not against S. epidermidis in which, surprisingly, these metabolites stimulated biofilm formation (between 35% and 1,200%). Binary combinations of cranberry extract and resveratrol with genistein, protocatechuic or p-hydroxibenzoic acid enhanced the stimulatory effect on S. epidermidis biofilm formation and maintained or even increased S. aureus anti-biofilm activity.

show abstract

Section: Antimicrobial Activity Of Non-toxic Plant-derived Compoundsmentioning

confidence: 94%

Non-toxic plant metabolites regulateStaphylococcusviability and biofilm formation: a natural therapeutic strategy useful in the treatment and prevention of skin infections

et al. 2014

View full text Add to dashboard Cite

show abstract

“…From here, they enter to the food chain and cause physiological, pharmacological, pathological and toxicological health hazards (Gould ; Venkitanarayanan et al . ).…”

Section: Introductionmentioning

confidence: 97%

“…Some of the antibiotics are quickly excreted from the animal body, whereas some of them are not metabolized. From here, they enter to the food chain and cause physiological, pharmacological, pathological and toxicological health hazards (Gould 2008;Venkitanarayanan et al 2013).…”

Section: Introductionmentioning

confidence: 99%

Impact of Various Processing Techniques on Dissipation Behavior of Antibiotic Residues in Poultry Meat

Khan

Randhawa

Butt

et al. 2015

Journal of Food Processing and Preservation

View full text Add to dashboard Cite

Instant research was planned to study the dissipation behavior of antibiotic residues in chicken meat using various heat‐processing treatments. Purposely, poultry birds were procured and administered with antibiotics for a period of 42 days. Chicken meat, after slaughtering, was processed through boiling, grilling, microwaving and roasting techniques to assess the impact of processing on antibiotic (enrofloxacin, ciprofloxacin, oxytetracycline and doxycycline) residues through high‐performance liquid chromatography technique. From the obtained results, antibiotics were dissipated as a function of processing technologies. Specifically, enrofloxacin residues were reduced with roasting (68.76%) and boiling (68.18%) against unprocessed meat, while grilling (33.34%) was least effective in reducing the antibiotic residues. Overall, roasting method was effective in reducing antibiotic residues. However, boiling and microwave processing were statistically at par with each other. Moreover, oxytetracycline was decreased significantly in microwave processing (72.37%). It is suggested that the whole food chain needs to be restructured, and stakeholder should work together in controlling the use of antibiotics. Practical Applications Although poultry industry is the leading source of rapid protein to consumers, yet antibiotic residues have emerged as a leading public health concern in the developing countries. There is some unusual high prevalence of antibiotic residues in poultry feed that poses serious health risk to community. Additionally, a little research has been carried out regarding the impact of processing conditions on antibiotic residues in poultry meat with special reference to food safety situation in developing countries. In the present study, the authors have explored the impact of various food processing techniques/methods on the dissipation behavior of antibiotic residues in poultry meat. From the study findings, it is suggested that processing resulted in significant reduction in antibiotic residues. Specifically, roasting emerged as an effective approach with maximum dissipation of antibiotic residues as compared with other processing methods such as boiling, grilling and microwaving.

show abstract

“…Several natural alternatives such as marine products, organic acids, microbiota enhancers, probiotics, prebiotics, and herbal products have been evaluated as feed additives in poultry (Venkitanarayanan et al, 2013). Among these, prebiotics have been shown to selectively increase the growth of beneficial microbes and inhibit pathogen colonization.…”

Section: Introductionmentioning

confidence: 99%

Feed Supplementation with Red Seaweeds, Chondrus crispus and Sarcodiotheca gaudichaudii, Reduce Salmonella Enteritidis in Laying Hens

et al. 2017

View full text Add to dashboard Cite

Salmonella Enteritidis is vertically transmitted to eggs from laying hens through infected ovaries and oviducts. S. Enteritidis can also penetrate the eggshell from contaminated feces. Reducing S. Enteritidis in laying hens is vital to provide safer eggs and minimize the spread of salmonellosis to humans. Antibiotics have been widely used to control bacterial diseases in broilers and laying hens. However, there is a major concern that the use of antibiotics leads to the development of antibiotic resistance and adverse effects on microbiota of the treated birds. Thus, there is an interest in developing alternatives to antibiotics, such as dietary prebiotics. In the present study, feed supplemented with the red seaweeds: Chondrus crispus (CC) or Sarcodiotheca gaudichaudii (SG), was offered to laying hens late in production to control S. Enteritidis. Diets contained one of the following; 2% or 4% Chondrus crispus (CC2, and CC4, respectively) or Sarcodiotheca gaudichaudii (SG2 and SG4, respectively). Chlortetracycline was used in the positive control diet. During week-4, 48 birds were orally challenged with 2 × 109 CFU/mL of S. Enteritidis. Eggs and fecal samples were collected 1, 3, 5, and 7 days’ post inoculation. Birds were euthanized and organs (ceca, ovary, liver, and spleen) were sampled and analyzed for the presence of S. Enteritidis, 7 days’ post inoculation. Results showed that seaweed reduced the negative effect on body weight and egg production in S. Enteritidis-challenged laying hens. Analysis of fecal samples showed that the antibiotic (CTC) reduced S. Enteritidis in the intestinal tract and fecal samples, 3 days’ post inoculation. Fecal samples from Chlortetracycline and CC4 supplemented birds tested negative for S. Enteritidis on days 5 and 7 post inoculation (lowest detection limit = 10-1). S. Enteritidis colonization in the ceca was also significantly reduced in birds fed CC (4%) and Chlortetracycline. Blood serum profiles revealed that there were no significant differences in serum aspartate aminotransferase (AST) and sodium. However, the level of serum immunoglobulin (IgA) was higher in the CC4 treatment. The relative abundance of Lactobacillus acidophilus was significantly higher in CC4 while, the abundance of the pathogenic bacteria, Clostridium perfringens and Salmonella Enteritidis were reduced compared to control. Results indicate that feed supplemented with 4% CC is effective in providing protection against Salmonella Enteritidis colonization in laying hens.

show abstract

Use of plant-derived antimicrobials for improving the safety of poultry products

Cited by 50 publications

References 92 publications

Non-toxic plant metabolites regulateStaphylococcusviability and biofilm formation: a natural therapeutic strategy useful in the treatment and prevention of skin infections

Non-toxic plant metabolites regulateStaphylococcusviability and biofilm formation: a natural therapeutic strategy useful in the treatment and prevention of skin infections

Impact of Various Processing Techniques on Dissipation Behavior of Antibiotic Residues in Poultry Meat

Feed Supplementation with Red Seaweeds, Chondrus crispus and Sarcodiotheca gaudichaudii, Reduce Salmonella Enteritidis in Laying Hens

Contact Info

Product

Resources

About