2014
DOI: 10.1177/1060028014553007
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Use of Nonsteroidal Anti-inflammatory Drugs in Colorectal Surgery

Abstract: Nonsteroidal anti-inflammatory drug (NSAID) use is recognized as a key component of the Enhanced Recovery After Surgery protocols and is systematically recommended in colorectal surgery to optimize perioperative care. However, a red flag about this practice has been raised because clinical studies have recently pointed out an increased risk of anastomotic leak after colorectal surgery following NSAID administration. Therefore, we used the Bradford Hill criteria to examine this potential relationship and conclu… Show more

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Cited by 3 publications
(1 citation statement)
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“…Along with opioid-sparing effects, NSAIDs are associated with negative effects such as possible increased risk of bleeding and acute renal failure (Blouin & Rhainds, 2014;Shukla, Rai, Prasad, & Agarwal, 2017;Van Koughnett & Wexner, 2014;Warth et al, 2016). Patients should be carefully evaluated for potential risks for adverse events with NSAIDs.…”
Section: Rationalementioning
confidence: 99%
“…Along with opioid-sparing effects, NSAIDs are associated with negative effects such as possible increased risk of bleeding and acute renal failure (Blouin & Rhainds, 2014;Shukla, Rai, Prasad, & Agarwal, 2017;Van Koughnett & Wexner, 2014;Warth et al, 2016). Patients should be carefully evaluated for potential risks for adverse events with NSAIDs.…”
Section: Rationalementioning
confidence: 99%