Use of Natural Components Derived from Oil Seed Plants for Treatment of Inflammatory Skin Diseases

Abstract

The incidence of inflammatory skin diseases is increasing, so the search for relevant therapeutics is of major concern. Plants are rich in phytochemicals which can alleviate many symptoms. In this review, we concentrate on compounds found in the seeds of widely cultivated plants, regularly used for oil production. The oils from these plants are often used to alleviate the symptoms of inflammatory diseases through synergetic action of unsaturated fatty acids and other phytochemicals most commonly derived from the terpenoid pathway. The knowledge of the chemical composition of oil seeds and the understanding of the mechanisms of action of single components should allow for a more tailored approach for the treatment for many diseases. In many cases, these seeds could serve as an efficient material for the isolation of pure phytochemicals. Here we present the content of phytochemicals, assumed to be responsible for healing properties of plant oils in a widely cultivated oil seed plants and review the proposed mechanism of action for fatty acids, selected mono-, sesqui-, di- and triterpenes, carotenoids, tocopherol and polyphenols.

Vegetable Butters and Oils as Therapeutically and Cosmetically Active Ingredients for Dermal Use: A Review of Clinical Studies

“…Dermally applied free fatty acids have also been shown to penetrate into the stratum corneum and enhance the penetration of other substances ( Nanayakkara et al, 2005 ). Vegetable butters and oils can therefore be used to improve skin wound healing ( Alves et al, 2019 ; Poljšak et al, 2019 ), ameliorate the severity of dermatitis ( Desai, 2017 ; Hou et al, 2017 ), alleviate symptoms of inflammatory conditions ( Styrczewska et al, 2019 ), etc.…”