Use of magnetic resonance imaging to identify changes in cerebral blood flow in epilepsia partialis continua

Fish, D. R.; Brooks, David J.; Young, I. R.; Bydder, Graeme M.

doi:10.1002/mrm.1910080215

Cited by 14 publications

(2 citation statements)

References 5 publications

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“…Dynamic susceptibility MRI has proven to be of immense diagnostic value in several disorders, including brain tumors (31), ischemic cerebrovascular diseases (4), focal hyperperfusion during status epilepticus (32, 33), and abnormal cerebral blood volume in interictal and ictal epilepsy (23). Perfusion MRI using the arterial spin labeling technique has also been proven to have diagnostic value in ischemic cerebrovascular diseases (5).…”

Section: Discussionmentioning

confidence: 99%

Perfusion-weighted imaging of interictal hypoperfusion in temporal lobe epilepsy using FAIR-HASTE: Comparison with H215O PET measurements

et al. 2001

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To detect perfusion abnormalities in areas of high magnetic susceptibility in the brain, an arterial spin‐labeling MRI technique utilizing flow‐sensitive alternating inversion recovery (FAIR) and half‐Fourier single shot turbo spin‐echo (HASTE) for spin preparation and image acquisition, respectively, was developed. It was initially tested in a functional study involving visual stimulation, and was able to detect significant activation with an increase (approximately 70%) in relative cerebral blood flow. Subsequently, it was applied in a clinical situation in eight patients with temporal lobe epilepsy (TLE). The perfusion‐weighted images obtained showed no susceptibility artifacts even in the region of the inferior temporal lobe and were able to detect interictal hypoperfusion in TLE. The results were compared with those derived from H215O PET perfusion imaging in each patient. A statistically significant correlation (r = 0.75, P < 0.05) was found between results acquired from these two modalities. Magn Reson Med 45:431–435, 2001. © 2001 Wiley‐Liss, Inc.

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Section: Discussionmentioning

confidence: 99%

Perfusion-weighted imaging of interictal hypoperfusion in temporal lobe epilepsy using FAIR-HASTE: Comparison with H215O PET measurements

et al. 2001

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“…Functional magnetic resonance imaging (fMRI) has disclosed increased perfusion in focal brain areas during focal seizures [5][6][7] . The unpredictable nature of seizures, however, restricts its clinical application to those rare subjects who have frequent subcontinuous SUMMARY -We performed functional magnetic resonance imaging (fMRI) in a 30-year-old man with idiopathic partial epilepsy with occipital spikes whose scalp EEG activity was characterized by persistent epileptiform discharges on eye closure, ceasing upon eye opening.…”

Section: Introductionmentioning

confidence: 99%

f-MRI in Epilepsy with Spike and Wave Activity Evoked by Eye Closure: Different Bold Activation in a Patient with Idiopathic Partial Epilepsy with Occipital Spikes and a Control Group

et al. 2008

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We performed functional magnetic resonance imaging (fMRI) in a 30-year-old man with idiopathic partial epilepsy with occipital spikes whose scalp EEG activity was characterized by persistent epileptiform discharges on eye closure, ceasing upon eye opening. We compared BOLD activation in the patient and in a control group of three normal volunteers. f-MRI showed that occipital cortex and frontal areas were activated in relation to eye movement in normal subjects during eye opening but not during eye closing. While persistent interictal spike and wave activity was present over the posterior and anterior scalp in the patient upon eye closing, f-MRI showed bilateral activation of the parietal and temporal regions. This fMRI study documents the activation of posterior and temporal areas related to continuous intercritical spikes evoked by eye closure, which are diffuse over the scalp. This activation was absent in the control group during eye closure.

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Use of magnetic particles for sensitizing MR images to blood flow

Hardy

Bronskill

Belanger

et al. 1991

Magnetic Resonance Imaging

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Magnetic resonance (MR) images made with the IVIM (intravoxel incoherent motion) technique for demonstrating tissue microcirculation are limited in sensitivity because of the small volume of blood involved. This limitation may be overcome by incorporating magnetic particles into the flow. The magnetic perturbation caused by the particles extends beyond the walls of the capillary and affects a much larger volume than that of the flowing material. Imaging experiments conducted with an artificial capillary system for renal dialysis, containing large magnetic particles, showed that signal intensity decreased with increasing flow rate through the dialysis bundle and with increasing particle concentration. Predictions of the effect based on a theoretical model of spin dephasing in the field of a magnetic dipole agreed with the experimental data. The results hold promise for development of the technique in vivo.

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Use of magnetic resonance imaging to identify changes in cerebral blood flow in epilepsia partialis continua

Cited by 14 publications

References 5 publications

Perfusion-weighted imaging of interictal hypoperfusion in temporal lobe epilepsy using FAIR-HASTE: Comparison with H215O PET measurements

Perfusion-weighted imaging of interictal hypoperfusion in temporal lobe epilepsy using FAIR-HASTE: Comparison with H215O PET measurements

f-MRI in Epilepsy with Spike and Wave Activity Evoked by Eye Closure: Different Bold Activation in a Patient with Idiopathic Partial Epilepsy with Occipital Spikes and a Control Group

Use of magnetic particles for sensitizing MR images to blood flow

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