Use of IV contrast media in radiotherapy planning CT scans: A UK audit

Williams, Kenneth M.; Probst, Heidi

doi:10.1016/j.radi.2016.06.006

Cited by 8 publications

(17 citation statements)

References 13 publications

(23 reference statements)

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“…This inconsistency is in keeping with a recent survey of radiotherapy centres by Williams and Probst. 21 This makes correlation between guidance and practice almost impossible for clinical practitioners. This survey identified that the most common guidelines in use across the UK were those published by the RCR.…”

Section: Discussionmentioning

confidence: 99%

“…A recent survey of radiotherapy centre CT provision also demonstrated variation between testing all patients vs testing those at high risk only. 21 Conclusive evidence that renal function testing is required only in patients at high risk would make a significant impact on workloads, thereby streamlining CT services and waiting times for scan. Unfortunately, this evidence has yet to be produced and the question still remains should blood tests be performed on everyone or on patients at high risk only?…”

Section: Discussionmentioning

confidence: 99%

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Strategies for assessing renal function prior to outpatient contrast-enhanced CT: a UK survey

Harris

Snaith

Clarke

2016

BJR

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The wide variation in practice reflects inconsistencies in published guidance. Evidence-based consensuses of which patients to test and subsequent risk thresholds will aid clinicians identify those patients in which the risk of CI-AKI is clinically significant but manageable. There is also a need to determine the value of the various prophylactic strategies, follow-up regimen and efficient service delivery pathways. Advances in knowledge: This survey has identified that further work is required to define which patients are high risk, confirm those which require renal function testing prior to contrast administration and how best to manage patients at risk of CI-AKI. The role of new technologies within this service delivery pathway requires further investigation.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Strategies for assessing renal function prior to outpatient contrast-enhanced CT: a UK survey

Harris

Snaith

Clarke

2016

BJR

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“…Some guidelines identifying management standards were issued in 2010 and updated in 2015 [47], and stated that risk factors should be assessed for all patients prior to intravenous contrast administration, glomerular filtration rate should be assessed for all non-emergency patients, and a minimum rate of >60 ml/min/1.73m2 is recommended.…”

Section: Resultsmentioning

confidence: 99%

Iodine-induced Nephropathy in Patients with Oncological Disorders Treated with Chemotherapy

2020

Rev.Chim.

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Cancer represents the second most important cause of death and morbidity in Europe, with more than 3.7 million new cases and 1.9 million deaths reported each year. Computed tomography plays a fundamental role in the management of oncology patients, and the superior diagnostic value that contrast-enhanced images offer is frequently critical. It is well recognized that iodinated contrast media have a cytotoxic effect, and this is felt to be one of the mechanisms responsible for contrast-induced nephrotoxicity. The study aims to analyze the correlation between administration of iodinated contrast substance (namely, Iohexol) and serum creatinine values 48 hours afterwards in patients with oncological conditions undergoing chemotherapy, which perform CT examinations (observational study). Keywords: CT, contrast media induced nephropathy, chemotherapy

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“…Despite these published recommendations, there are variations in the routine application of IVC in clinical practice in RT. Clinical experience and expertise, clinical trial protocols and/or consensus contouring atlases are factors attributed to these variations [11,14,15]. In 2008, Kim et al found that 76% of the responding centres in a UK wide study used IVC for at least one of the nine recommended cancer sites, no department administered IVC for all nine of the recommended sites and 54% wished to administer it to additional tumour sites [15].…”

Section: Introductionmentioning

confidence: 99%

“…In 2008, Kim et al found that 76% of the responding centres in a UK wide study used IVC for at least one of the nine recommended cancer sites, no department administered IVC for all nine of the recommended sites and 54% wished to administer it to additional tumour sites [15]. In 2016, Williams et al published a follow-up study and found that 98% of these centres deliver IVC to all nine recommended tumour sites [14], but no department administered contrast to all of the RCR suggested sites Some recommendations from the study stated concerns for patient safety during IVC procedure and the need for definitive regulations and guidelines to ensure patient safety [14].…”

Section: Introductionmentioning

confidence: 99%

Intravenous contrast media in radiation therapy planning computed tomography scans – Current practice in Ireland

Minogue

Gillham²,

Kearney

et al. 2019

Technical Innovations & Patient Support in Radiation Oncolo

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Introduction: While Computerised Tomography (CT) remains the gold standard in radiation therapy (RT) planning, inferior soft tissue definition remains a challenge. Intravenous contrast (IVC) use during CT planning can enhance soft tissue contrast optimising Target Volume (TV) and Organ at Risk visualisation and delineation. Despite this known benefit, there are no guidelines for when and how to use IVC in RT planning scans in Ireland. Aim: The study aims to examine the patterns of practice in relation to the use of IVC in RT planning scans in Ireland and to determine the level of compliance with international guidelines. Radiation Therapists (RTT) IVC training will also be investigated. Materials and methods: An anonymised online survey was designed based on previously-reported literature. This was distributed to all RT departments in Ireland. The survey contained open, closed and Likert scale questions that investigated IVC practices in each department. Results: 75% (n = 9/12) of Irish departments responded. All responding departments reported using IVC. RTTs cannulated patients in 67% (n = 6/9) of the departments and administration contrast in all departments. Variations from recommended guidelines were found in disease sites where IVC was routinely used and in the assessment of renal functioning prior to contrast administration. IVC training varied in duration and number of supervised procedures required to fulfill competencies. Conclusion: IVC is used extensively in Irish RT departments. There are variations in IVC practice between departments and with international recommended guidelines.

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Use of IV contrast media in radiotherapy planning CT scans: A UK audit

Cited by 8 publications

References 13 publications

Strategies for assessing renal function prior to outpatient contrast-enhanced CT: a UK survey

Strategies for assessing renal function prior to outpatient contrast-enhanced CT: a UK survey

Iodine-induced Nephropathy in Patients with Oncological Disorders Treated with Chemotherapy

Intravenous contrast media in radiation therapy planning computed tomography scans – Current practice in Ireland

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