Iodine-induced Nephropathy in Patients with Oncological Disorders Treated with Chemotherapy

Abstract

Cancer represents the second most important cause of death and morbidity in Europe, with more than 3.7 million new cases and 1.9 million deaths reported each year. Computed tomography plays a fundamental role in the management of oncology patients, and the superior diagnostic value that contrast-enhanced images offer is frequently critical. It is well recognized that iodinated contrast media have a cytotoxic effect, and this is felt to be one of the mechanisms responsible for contrast-induced nephrotoxicity. The study aims to analyze the correlation between administration of iodinated contrast substance (namely, Iohexol) and serum creatinine values 48 hours afterwards in patients with oncological conditions undergoing chemotherapy, which perform CT examinations (observational study). Keywords: CT, contrast media induced nephropathy, chemotherapy