Use of Innovative (Micro)Extraction Techniques to Characterise <scp><i>Harpagophytum procumbens</i></scp> Root and its Commercial Food Supplements

Diuzheva, Alina; Carradori, Simone; Andruch, Vasiľ; Locatelli, Marcello; Luca, Elisa De; Tiecco, Marcello; Germani, Raimondo; Menghini, Luigi; Nocentini, Alessio; Gratteri, Paola; Campestre, Cristina

doi:10.1002/pca.2737

Cited by 40 publications

(12 citation statements)

References 31 publications

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“…The available chemical fingerprint could be used to better correlate the biological activities with principal bioactive compounds, as recently highlighted by Diuzheva et al. () and Kabir, Locatelli, and Ulusoy (). Environmentally friendly and effective extraction procedures that fulfill green chemistry key‐principles are being developed and are available for different extraction procedures/devices.…”

Section: Extraction Proceduresmentioning

confidence: 99%

A Review on the Dietary Flavonoid Tiliroside

Grochowski

Locatelli

Granica

et al. 2018

Comp Rev Food Sci Food Safe

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Among flavonoid derivatives, tiliroside is a flavonoid contained in several edible plants or specific plant parts (fruits, leaves, or roots). These parts are often widely used as both food and medicines, in the treatment of various ailments and, in some cases, as food supplements. Considering the easy access to many publications concerning tiliroside and the lack of a review that summarizes the current progress in studies on its safety, efficacy, and presence in the plant kingdom, we present here a review paper on tiliroside and its principal derivatives. The paper also highlights the basic knowledge regarding this molecule, its derivatives, and the analytical approaches used for extraction and quantification, as well as reports on the biological activities against different key enzymes linked to various human diseases. The reported information is also devoted to highlighting the concept "learn from nature to discover new products," particularly in the development of new drugs, food supplements, and nutraceuticals, starting from a natural lead compound such as tiliroside and improving its biological activities (and selectivities) against a specific target for therapeutic purposes.

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Section: Extraction Proceduresmentioning

confidence: 99%

A Review on the Dietary Flavonoid Tiliroside

Grochowski

Locatelli

Granica

et al. 2018

Comp Rev Food Sci Food Safe

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“…However, organic solvents are often toxic, flammable, explosive, and poorly biodegraded. Thus, development of new sample-preparation techniques for extraction and analysis of plant compounds are necessary to ensure that high-quality herbal products are available for consumers worldwide (Huie 2002;Diuzheva et al 2017). Advances that are needed include reduction in organic solvent consumption and sample degradation, elimination of additional sample clean-up and concentration steps before chromatographic analysis, ease of automation, and improvement in extraction efficiency, selectivity, and/or kinetics.…”

Section: Introductionmentioning

confidence: 99%

Development of a Method Based on Natural Deep Eutectic Solvents for Extraction of Flavonoids from Food Samples

2017

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Natural deep eutectic solvents (NADES) are promising green solvents for the extraction of compounds from natural products. This is the first study to use a sample preparation method based on NADES for the extraction of flavonoids (rutin, hesperidin, neohesperidin, naringenin, naringin, quercetin, hesperetin, and chrysin) from fruits, vegetables, and spices. In total, 17 types of NADES based on choline chloride, acetylcholine chloride, choline tartrate, betaine, and carnitine with different compositions were tailored to test their extraction efficiency. Operational conditions such as water content in NADES and liquid/solid ratios were also studied. A response surface methodology was used for multivariate optimization of some extraction parameters. Efficient recovery of extracted flavonoids (higher than 70%) was achieved using a 30% water solution of acetylcholine chloride/lactic acid ratio (2:1) as an extraction solvent. Other conditions for SLE-NADES were as follows: liquid/solid ratio 3:1, extraction temperature 60°C, extraction time 30 min, and stirring speed 1400 rpm. Each extract was analyzed by UHPLC with UVand MS/ MS detection. The developed method was applied for analysis of flavonoids in fruits (cranberry, fruits of Lycium barbarum L., grape, plum, and orange peel), vegetables (onion and broccoli), and spices (mustard, rosemary, and black pepper).

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“…There is lack of published research on ultrasound assisted extraction (UAE) of bioactive materials from animal sources [ 8 , 9 , 10 ]. UAE can increase extraction efficiency and extraction rate particularly for aqueous extraction and lower processing temperatures can be applied for enhanced extraction of heat sensitive bioactive food components at lower processing temperatures [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Ultrasound Assisted Extraction in Conjugation with Aid of Actinidin on the Molecular and Physicochemical Properties of Bovine Hide Gelatin

et al. 2018

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Actinidin was used to pretreat the bovine hide and ultrasonic wave (53 kHz and 500 W) was used for the time durations of 2, 4 and 6 h at 60 °C to extract gelatin samples (UA2, UA4 and UA6, respectively). Control (UAC) gelatin was extracted using ultrasound for 6 h at 60 °C without enzyme pretreatment. There was significant (p < 0.05) increase in gelatin yield as the time duration of ultrasound treatment increased with UA6 giving the highest yield of 19.65%. Gel strength and viscosity of UAC and UA6 extracted gelatin samples were 627.53 and 502.16 g and 16.33 and 15.60 mPa.s, respectively. Longer duration of ultrasound treatment increased amino acids content of the extracted gelatin and UAC exhibited the highest content of amino acids. Progressive degradation of polypeptide chains was observed in the protein pattern of the extracted gelatin as the time duration of ultrasound extraction increased. Fourier transform infrared (FTIR) spectroscopy depicted loss of molecular order and degradation in UA6. Scanning electron microscopy (SEM) revealed protein aggregation and network formation in the gelatin samples with increasing time of ultrasound treatment. The study indicated that ultrasound assisted gelatin extraction using actinidin exhibited high yield with good quality gelatin.

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Use of Innovative (Micro)Extraction Techniques to Characterise Harpagophytum procumbens Root and its Commercial Food Supplements

Abstract: All commercial samples respected the European Pharmacopoeia monograph for this plant material, showing a harpagoside content ≥ 1.2%. Copyright © 2017 John Wiley & Sons, Ltd.

Cited by 40 publications

References 31 publications

A Review on the Dietary Flavonoid Tiliroside

A Review on the Dietary Flavonoid Tiliroside

Development of a Method Based on Natural Deep Eutectic Solvents for Extraction of Flavonoids from Food Samples

Effects of Ultrasound Assisted Extraction in Conjugation with Aid of Actinidin on the Molecular and Physicochemical Properties of Bovine Hide Gelatin

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