Use of in-office anesthesia during non-surgical radiofrequency collagen denaturation for stress urinary incontinence

Wells, W. Glen; Lenihan, J M A

doi:10.1185/030079907x188161

Cited by 7 publications

(5 citation statements)

References 13 publications

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“…However, in 2007 Wells and Lenihan [21] demonstrated that local anesthetic and oral sedation is a feasible alternative. Thirty-three women, all with SUI and urethral hypermobility, were enrolled in the study.…”

Section: Resultsmentioning

confidence: 99%

Radiofrequency for the treatment of stress urinary incontinence in women

Dillon¹,

Dmochowski

2009

Curr Urol Rep

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Stress urinary incontinence (SUI) is a socially disabling disorder that affects a large population of women around the world. Surgical treatments for SUI typically seek to recapitulate the support of the endopelvic fascia and reduce urethral hypermobility or improve urethral compressive forces. Radio-frequency energy is a potent tool for such treatment, as it is in other medical specialties. The development of transurethral approach techniques affords a major advantage because this nonsurgical procedure can be performed in an office setting with the use of an oral sedative and local anesthesia. The data collected to date suggest that radiofrequency treatment of SUI has promising efficacy and entails a minimal risk of adverse events. Further randomized studies with longer follow-up are needed to assess the ultimate role of this procedure in future urology practice.

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Section: Resultsmentioning

confidence: 99%

Radiofrequency for the treatment of stress urinary incontinence in women

Dillon¹,

Dmochowski

2009

Curr Urol Rep

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“…Wells and Lenihan reported on the feasibility of in-office anesthesia in patients undergoing transurethral radiofrequency treatment, employing preprocedure diazepam with a bilateral periurethral block using a total of 10 cc of 2% lidocaine [24]. Thirty-three women completed a visual analog scale (0 = no pain, 10 = terrible pain) immediately prior to discharge.…”

Section: Clinical Recommendations For Office-based Lower Urinary Tmentioning

confidence: 99%

Transurethral Radiofrequency Collagen Denaturation for Treatment of Female Stress Urinary Incontinence: A Review of the Literature and Clinical Recommendations

Lukban

2012

Obstetrics and Gynecology International

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Stress urinary incontinence is a prevalent condition in women with a significant negative effect on quality of life. Intervention includes behavioral modification, intravaginal devices, pelvic floor muscle exercises, biofeedback, functional electrical stimulation, and surgical procedures. We will review a new in-office procedure for the treatment of SUI that may serve as a viable nonsurgical option.

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“…The sham treatment differed in that the probe contained no needle electrodes and no RF energy was being delivered, even though the modifi ed sham generator appeared and sounded like the actual RF treatment generator. Although this procedure is now typically performed using local anesthesia [ 28 ], all procedures in this study were performed under conscious sedation in an outpatient setting. The entire procedure, including positioning and treatment, required about 20 to 30 minutes.…”

Section: Randomized Sham-controlled Trialmentioning

confidence: 99%

Transurethral collagen denaturation for women with stress urinary incontinence

Appell

2008

Curr Urol Rep

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Transurethral collagen denaturation was approved by the US Food and Drug Administration in 2005 for the nonsurgical treatment of stress urinary incontinence in women. In this procedure, controlled, nonablative radiofrequency energy applied through a transurethral probe produces microscopic submucosal sites of collagen denaturation, resulting in reduced tissue compliance. Treatment is administered in about 30 minutes in an outpatient setting without incisions, general anesthesia, or use of cystoscopy or other visualization. The safety and efficacy of this treatment were demonstrated in a pilot trial in 41 women and then in a subsequent 12-month sham procedure-controlled trial in more than 170 women. Ongoing clinical trials include a 3-year, open-label durability study and an evaluation of this technique in women who have failed prior surgical intervention. To date, patients who received transurethral collagen denaturation have experienced improvements in quality of life and in Valsalva leak point pressure. This procedure presents a beneficial nonsurgical treatment option for women with stress urinary incontinence.

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Use of in-office anesthesia during non-surgical radiofrequency collagen denaturation for stress urinary incontinence

Abstract: The results of this trial were similar to those of larger, sham-controlled studies using intravenous conscious sedation and showed non-surgical RF collagen denaturation to be feasible, safe, and effective when performed using in-office anesthesia.

Cited by 7 publications

References 13 publications

Radiofrequency for the treatment of stress urinary incontinence in women

Radiofrequency for the treatment of stress urinary incontinence in women

Transurethral Radiofrequency Collagen Denaturation for Treatment of Female Stress Urinary Incontinence: A Review of the Literature and Clinical Recommendations

Transurethral collagen denaturation for women with stress urinary incontinence

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