Use of Imipramine in Children with Intractable Asthma and Psychiatric Disorders: A Warning

Kanner, Andrés M.; Klein, Rachel G.; Rubinstein, Boris; Mascia, Armond V.

doi:10.1159/000288157

Cited by 6 publications

(1 citation statement)

References 9 publications

(9 reference statements)

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“…Finally, side effects have been reported when asthma medications are utilized in conjunction with psychiatric medications. Kanner et al (1989) have raised this concern when a pilot trial of psychiatric medication with a group of asthmatics was terminated due to medical complications. Koenig (1988) reviewed asthma treatment with inhaled corticosteroids and, despite the case of a 5-year-old girl who became acutely psychotic with high doses of corticosteroids, concluded that these medications were safe.…”

Section: Medication Effectsmentioning

confidence: 99%

Neuropsychological dysfunction in asthmatic children

Annett

Bender

1994

Neuropsychol Rev

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Neuropsychological dysfunction associated with pediatric asthma is reviewed. Significant methodological confounds associated with clinical research, including problems with the objective measure of asthma, are prevalent in many studies. Most evidence does not support the belief that asthma alone results in homogeneous neuropsychological compromise. Studies of adverse reactions to asthma medications indicate medication-specific effects including slight improvements in some aspects of neuropsychological functioning, such as attention, and deficiencies in other aspects of neuropsychological functioning, such as memory. The acute neuropsychological effects of various medication regimens appears to be reversible with cessation of the asthma medication under suspicion, although no data yet exist regarding the long-term effects of therapeutic dosages of asthma medications upon a developing nervous system. The hypothetical effects of asthma on school performance have been related to non-neuropsychological variables such as a child's socioeconomic status, though there is also evidence suggesting that poorly controlled asthma is related to learning problems. Implications for pediatric neuropsychologists are discussed.

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Section: Medication Effectsmentioning

confidence: 99%