Use of Gabapentin and Pregabalin for Hand Surgery Patients

Brunton, Lance M.; LaPorte, Dawn M.

doi:10.1016/j.jhsa.2012.04.013

Cited by 8 publications

(10 citation statements)

References 19 publications

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“…[21][22][23] It has ≥90% oral bioavailability, is minimally metabolized, and has a half-life of 6.3 hours. [7][8][9][10][11][12][13][15][16][17][18][19][20][21][23][24][25][26][27] Effective postoperative pain control is also dependent on the timing of analgesic administration. 5,13 It has been methodically compared with other analgesics/anti-inflammatories and placebo in a variety of surgical procedures, from photorefractive keratectomy to transperitoneal nephrectomy.…”

Section: Discussionmentioning

confidence: 99%

Perioperative Pregabalin for Attenuation of Postoperative Pain After Eyelid Surgery

Wei¹,

Davies

Hink

et al. 2015

Ophthalmic Plastic &Amp; Reconstructive Surgery

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Section: Discussionmentioning

confidence: 99%

Perioperative Pregabalin for Attenuation of Postoperative Pain After Eyelid Surgery

Wei¹,

Davies

Hink

et al. 2015

Ophthalmic Plastic &Amp; Reconstructive Surgery

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“…This was in line with evidence-based recommendations for neurogenic pain. 43,44 By only prescribing opioids when indicated, ie, not for neurogenic pain, surgeons can assist in the goal of reducing opioid misuse and abuse. 17 There are several weaknesses in this study.…”

Section: Discussionmentioning

confidence: 99%

Enrollment in Treatment at a Specialized Pain Management Clinic at a Tertiary Referral Center after Surgery for Ulnar Nerve Compression: Patient Characteristics and Outcome

Giöstad

Räntfors

Nyman

et al. 2021

Journal of Hand Surgery Global Online

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To study patients who enroll in treatment at a specialized pain management clinic at a tertiary referral center following ulnar nerve decompression. Methods: Data from medical charts and postoperative questionnaires were collected for all patients after surgery for ulnar nerve compression at the elbow from 2011 to 2014 (n ¼ 173) at a tertiary referral center. Differences in characteristics between patients who enrolled in treatment at the pain management clinic (study group, n ¼ 26) and the rest of the patients (reference group, n ¼ 147) were analyzed. The study group was further evaluated using questionnaires from the Swedish Quality Registry for Pain Rehabilitation (SQRP) and regarding outcome of pain treatment. Results: The study group was characterized by prior pain conditions, earlier contact with a pain management clinic, and high degrees of kinesiophobia, depression/anxiety, low quality of life, and low life satisfaction. These patients had significantly higher postoperative Disabilities of the Arm, Shoulder, and Hand (DASH) scores, were significantly younger, and had bilateral surgery significantly more often than the reference group. For patients with unilateral surgery, simple decompression was significantly more common in the reference group. The most common treatments at the clinic were antidepressants and anticonvulsants for neurogenic pain. In 5 of 26 patients, pain relief, or pain reduction was the documented reason for discharge. Conclusions: Pain is a relevant outcome measure for ulnar nerve decompression among complicated cases at a referral center. Severe postoperative pain is connected to higher disability, reduced life satisfaction, and overall low health status. This study maps out characteristics of patients who postoperatively enroll in treatment at a specialized pain management clinic following ulnar nerve decompression. Further studies are needed to define predictive factors for such pain.

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“…However, some promising off-label evidence was shown in lumbar spine surgery, shoulder surgery, and adult reconstruction. 55 , 56 Gabapentin is considered less potent than pregabalin, but it has a generic formulary, so it is more cost-effective. Side effects are dizziness, somnolence, ataxia, headache, and edema, which are more pronounced in elderly and renal-impaired patients.…”

Section: Recommendationsmentioning

confidence: 99%

Evidenced-Based Opioid Prescribing Recommendations Following Hand and Upper-Extremity Surgery

Adams

Ilyas²

2022

Journal of Hand Surgery Global Online

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Use of Gabapentin and Pregabalin for Hand Surgery Patients

Cited by 8 publications

References 19 publications

Perioperative Pregabalin for Attenuation of Postoperative Pain After Eyelid Surgery

Perioperative Pregabalin for Attenuation of Postoperative Pain After Eyelid Surgery

Enrollment in Treatment at a Specialized Pain Management Clinic at a Tertiary Referral Center after Surgery for Ulnar Nerve Compression: Patient Characteristics and Outcome

Evidenced-Based Opioid Prescribing Recommendations Following Hand and Upper-Extremity Surgery

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