Use of DNA Fingerprinting to Detect Genotoxic Effects

Evaluation of genotoxicity of Pseudevernia furfuracea (L.) Zopf by RAPD analysis

“…RAPD analysis can help determine not only the mutational effects of heavy metals but also the mutational effects of organic and inorganic genotoxic agents on different organisms (Labra et al, 2003). Fingerprinting methods such as RAPD and AFLP are sensitive, effective, relatively cheap and simple techniques as they can be applied to various organisms directly from their DNA and they help to analyze the whole genome (Savva, 1996(Savva, , 1998Conte et al, 1998;Labra et al, 2003;Liu et al, 2005). They are quite useful, especially for pollution studies as they can compare polluted and nonpolluted samples at the same time and in relatively shorter periods (Liu et al, 2005).…”

QUALITATIVE ASSESSMENT OF CADMIUM STRESS USING GENOME TEMPLATE STABILITY IN Hordeum vulgare

“…The changes in DNA caused by genotoxic chemicals may be monitored using different biomarker assays both at biochemical and molecular level (Savva, 1998).…”

Determination of DNA Methylation Levels with CRED-RA Technique in the Genome of Sunflower Seedlings (Helianthus annuus L.) Subjected to Zinc Stress

“…Heavy metals also cause damage to most of the functional biomolecules including membrane lipids and this results in increase of some reactive oxygen types which cause oxidative stress [3]. This situation occurs as a results of treating organisms with some chemical, biological and physical agents that leads to damages in their genetic materials [4][5][6][7]. Zinc is a microelement which should be taken in very less amounts by plants, animals and humans.…”