Use of Dermal Regenerative Peripheral Nerve Interfaces as a Prophylactic Tool for Neuroma Prevention in Digit Amputation

Holan, BA Cole A.; Bashour, Laura; Schafer, BS Helen A.; O’Connor, BS Kaylee M.; Egeland, Brent M.; Kelley, Brian P.

doi:10.1097/01.gox.0000799600.92164.ee

Cited by 1 publication

(1 citation statement)

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“…25 In another small retrospective study evaluating hand patients undergoing elective amputations with prophylactic DS-RPNI, the authors found no digital neuromas in 14 treated digits compared to 2 neuromas in 19 digits (5.6%) in the control group. 26 Additionally, the authors found no difference in complications or infections between the two groups. Results for the treatment of neuropathic pain in the knee and ankle with neurectomy combined with DS-RPNI are also quite promising (unpublished data).…”

Section: Clinical Outcomesmentioning

confidence: 89%

Management of Neuropathic Pain with Neurectomy Combined with Dermal Sensory Regenerative Peripheral Nerve Interface (DS-RPNI)

Hespe,

Brown

2024

Semin Plast Surg

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Neuropathic pain affects a large percentage of the U.S. population and leads to tremendous morbidity. Numerous nonsurgical and surgical treatments have been utilized to try and manage neuropathic pain with varying degrees of success. Recent research investigating ways to improve prosthetic control have identified new mechanisms for preventing neuromas in both motor and sensory nerves with free muscle and dermal grafts, respectively. These procedures have been used to treat chronic neuropathic pain in nonamputees, as well, in order to reduce failure rates found with traditional neurectomy procedures. Herein, we focus our attention on Dermal Sensory-Regenerative Peripheral Nerve Interfaces (DS-RPNI, free dermal grafts) which can be used to physiologically “cap” sensory nerves following neurectomy and have been shown to significantly decrease neuropathic pain.

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Section: Clinical Outcomesmentioning

confidence: 89%