2004
DOI: 10.1373/clinchem.2004.036822
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Use of Computer Simulation to Study Impact of Increasing Routine Test Volume on Turnaround Times of STAT Samples on ci8200 Integrated Chemistry and Immunoassay Analyzer

Abstract: Reactive oxygen species are highly reactive molecules and have been implicated in the pathophysiology of many diseases, including diabetes mellitus, cancer, rheumatoid arthritis, and cardiovascular, renal, inflammatory, infectious, and neurologic diseases (1, 2 ). Cells and biological fluids have an array of protective antioxidant mechanisms, both for preventing the production of free radicals and for repairing oxidative damage (3 ). These antioxidant systems include enzymes, macromolecules, and small molecule… Show more

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Cited by 6 publications
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“…In addition to the previous workflow analysis, we simulated the laboratory workflow processes of the two molecular platforms (a random-access instrument using the Xpert MRSA assay and a batching capability instrument using the LightCycler MRSA Advanced Test) using a discrete event simulator to achieve an objective, unbiased appreciation of laboratory efficiency parameters, including test throughput (number of samples that can be tested per day), expected turnaround times, and labor utilization. iGrafx Process 2007 for Six Sigma discrete event simulation software version 1 (Corel Corp., Tualatin, OR) was used to develop simulation models for both molecular processes to allow quantitative determination of the efficiency parameters, described in detail by Mohammad et al 26,27 Site 1 most frequently tested samples as they arrived at the laboratory and did not batch as frequently as sites 2 and 3. Sites 2 and 3 used the eight-dock GeneXpert system.…”
Section: Workflow Simulation Analysismentioning
confidence: 99%
“…In addition to the previous workflow analysis, we simulated the laboratory workflow processes of the two molecular platforms (a random-access instrument using the Xpert MRSA assay and a batching capability instrument using the LightCycler MRSA Advanced Test) using a discrete event simulator to achieve an objective, unbiased appreciation of laboratory efficiency parameters, including test throughput (number of samples that can be tested per day), expected turnaround times, and labor utilization. iGrafx Process 2007 for Six Sigma discrete event simulation software version 1 (Corel Corp., Tualatin, OR) was used to develop simulation models for both molecular processes to allow quantitative determination of the efficiency parameters, described in detail by Mohammad et al 26,27 Site 1 most frequently tested samples as they arrived at the laboratory and did not batch as frequently as sites 2 and 3. Sites 2 and 3 used the eight-dock GeneXpert system.…”
Section: Workflow Simulation Analysismentioning
confidence: 99%