Use of complementary and alternative medicine by Korean patients with Parkinson's disease

Kim, Sung R.; Lee, Tai Y.; Kim, Mi S.; Lee, Myoung C.; Chung, Sun Ju

doi:10.1016/j.clineuro.2008.09.011

Cited by 62 publications

(59 citation statements)

References 20 publications

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“…Therefore, many Korean PD patients also experienced complementary or alternative medicine, especially Oriental Medicine, prior to modern medical therapy. Recently, Kim et al [37] reported that the proportion of PD patients who employed complementary or alternative medicine in Korea was higher than that in other countries, especially in the western hemisphere, despite higher costs and serious side effects.…”

Section: Discussionmentioning

confidence: 99%

Is There an Association between the Level of High-Sensitivity C-Reactive Protein and Idiopathic Parkinson’s Disease? A Comparison of Parkinson’s Disease Patients, Disease Controls and Healthy Individuals

et al. 2009

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Background: High-sensitivity C-reactive protein (hs-CRP) is a sensitive systemic marker of inflammation, and increased levels of hs-CRP are associated with inflammatory reactions. Microglia-mediated neuroinflammation has been hypothesized to play an important role in the pathogenesis of idiopathic Parkinson’s disease (PD). However, the clinical value of hs-CRP in PD is poorly defined. Therefore, we conducted this study to investigate the clinical value of hs-CRP in patients with PD. Methods: We examined 212 patients with de novo PD, 253 patients with acute ischemic cerebrovascular disease and 119 healthy subjects and investigated the differences in hs-CRP among these 3 groups. The PD group was classified into 4 subgroups according to the Hoehn and Yahr stage to investigate the relationship between hs-CRP and symptom severity. Results: There was no significant difference in the hs-CRP value between the PD and the ischemic cerebrovascular disease groups, but the subjects in the 2 disease groups demonstrated higher hs-CRP levels than those in the normal control group. A post-hoc analysis of the 4 PD subgroups showed no significant differences in hs-CRP values. In addition, this study demonstrated that the odds ratio of the PD group by hs-CRP was 2.037 (95% CI 1.180–3.517; p = 0.011). Conclusion: We suggest that our results could support the hypothesis that neuroinflammation contributed to the pathogenesis of PD and cautiously assume that elevated hs-CRP might have a clinical value as a risk factor for PD.

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Section: Discussionmentioning

confidence: 99%

Is There an Association between the Level of High-Sensitivity C-Reactive Protein and Idiopathic Parkinson’s Disease? A Comparison of Parkinson’s Disease Patients, Disease Controls and Healthy Individuals

et al. 2009

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“…4 Furthermore, patients using CAM hope to improve motor symptoms, fatigue, pain, and constipation. 5 Among CAM users with PD, 40% subjectively reported some improvement of their symptoms. 6 Studies conducted in the United States reported that 40% of patients with PD use at least one form of CAM, with the three most commonly used therapies being vitamins and herbs, massage therapy, and acupuncture.…”

Section: Introductionmentioning

confidence: 99%

Effects of Traditional Japanese Massage Therapy on Various Symptoms in Patients with Parkinson's Disease: A Case-Series Study

Donoyama

Ohkoshi

2012

The Journal of Alternative and Complementary Medicine

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“…Due to the limitations in these therapies, many PD patients seek complementary and alternative medicines (CAM) such as herbal medications. Approximately 40% of patients with PD in the United States, 39% of PD patients in the United Kingdom, and 76% of PD patients in Korea have used CAM (Ferry et al, 2002;Kim et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Neuroprotective effects of an herbal medicine, Yi-Gan San on MPP+/MPTP-induced cytotoxicity in vitro and in vivo

Doo

Kim

Park

et al. 2010

Journal of Ethnopharmacology

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Use of complementary and alternative medicine by Korean patients with Parkinson's disease

Cited by 62 publications

References 20 publications

Is There an Association between the Level of High-Sensitivity C-Reactive Protein and Idiopathic Parkinson’s Disease? A Comparison of Parkinson’s Disease Patients, Disease Controls and Healthy Individuals

Is There an Association between the Level of High-Sensitivity C-Reactive Protein and Idiopathic Parkinson’s Disease? A Comparison of Parkinson’s Disease Patients, Disease Controls and Healthy Individuals

Effects of Traditional Japanese Massage Therapy on Various Symptoms in Patients with Parkinson's Disease: A Case-Series Study

Neuroprotective effects of an herbal medicine, Yi-Gan San on MPP+/MPTP-induced cytotoxicity in vitro and in vivo

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