Use of Circular Dichroism to Determine the Absolute Configuration of a Pimarane Diterpenoid from the Southern African Sclerocroton integerrimus (Euphorbiaceae)

Abstract

From the stem bark and leaves of Sclerocroton integerrimus, eight compounds, including 17-hydroxy-ent-pimara-8(14),15-dien-3-one (1), were isolated. The structures of the compounds were determined on the basis of spectroscopic analysis. The absolute configuration of 17-hydroxy-ent-pimara-8(14),15-dien-3-one was confirmed from electronic circular dichroism studies.

Pseudopulchellol: A unique sesquiterpene-monoterpene derived C-25 terpenoid from the leaves of Croton pseudopulchellus Pax (Euphorbiaceae)

“…2). In addition, two structures of pseudopulchellol including the (+)-pinene ( 1) and (-)-pinene (1a) moieties were modelled following the protocol we have reported previously (Langat et al, 2014;Tembu et al, 2015) and their simulated ECD curves (Frisch et al, 2010) were compared to the experimental data for pseudopulchellol (Fig. 3) and this confirmed that the (+)-pinene moiety was a constituent pseudopulchellol.…”