Use of Chamomilla recutita in the Prevention and Treatment of Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation

Abstract

The results of this investigation will help nurses and other professionals in selecting the C recutita dosage used to manage oral mucositis in patients undergoing HSCT.

Efficacy of topical chamomile management vs. placebo in patients with oral lichen planus: a randomized double‐blind study

“…In these cases, it may be useful, if not essential, to adopt an alternative therapy. In this scenario, phytotherapy has been adopted as a therapeutic alternative to alleviate symptoms and improve OLP patients’ quality of life; it also offers the advantages of low cost, availability and absence of adverse effects …”

“…A variety of approaches have been used to treat oral lichen planus (OLP) including corticosteroids, retinoids, topical cyclosporine, antimicrobials azathioprine, calcineurin inhibitors and surgery .The main disadvantage of these treatments are their secondary effects . Several studies have investigated the application of chamomile for treating different oral diseases, particularly gingivitis, mucositis, aphthous stomatitis, but most were not randomized, controlled trials for the application of chamomile to treat OLP patients . The purpose of this study was to compare the clinical therapeutic efficacy of topical applications of chamomile for treating OLP vs. a placebo.…”

Oral Mucositis: Melatonin Gel an Effective New Treatment

“…They are applied as single infusions for gargling or topical application [65]. Of these, Matriciana camomilla , Salvia officinalis , Chimonanthus salicifolius , Aloe vera , Gentianae radix and date palm pollen have been used [65,66,67,68,69]. The anti-mucositis activity of different herbs might be due to inhibiting apoptosis and inflammation in GIT (gastrointestinal tract).…”

Evidence based complementary and alternative methods used in the prevention and treatment of oral mucositis in cancer:Literature review

“…Çalışmaların tamamında (%100) hastalarda çeşitli seviyelerde oral mukozit geliştiği saptanmıştır. Çalışmalar sonucunda hastalarda oral mukozit insidansında [4,5,6,7,8,26,28,29,30,31,32,33], oral mukozit şiddetinde azalma görüldüğü [6,8,22,24,26,27,28,32,33,34], oral mukozitin iyileşme sürecinin hızlandığı [6,24,33], oral mukozit ilişkili enfeksiyonlarda [2] ve hastane yatış süresinde azalma olduğu [2,7], ağrıyı azalttığı [2,5,28,34] ve opioid kullanımının azaldığı [29] ve yaşam kalitesinin arttığı [22] parenteral beslenme (TPN) kullanım süresinin kısaldığı [7] ve beslenme problemlerinin azaldığı [7,28] saptanmıştır.…”