Use of Cellutome for the healing of venous or mixed ulcers

Talvande, Blandine Vinceneux; Lallement, Priscille Carvalho; Safa, Gilles; Tollhupp, Julie Journet; Lembelembe, Jean-Paul; Blaise, S.; Maillard, H.

doi:10.1111/iwj.12966

Cited by 2 publications

(4 citation statements)

References 13 publications

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“…Zabieg ten znamiennie skraca czas gojenia, choć w Polsce wykonywany jest wyłącznie u pacjentów hospitalizowanych. Powszechnie wykorzystuje się dermatom lub wyspecjalizowane urządzenia do pobierania wysepek naskórka [18][19][20][21][22][23][24]. Zabiegi te muszą być jednak wykonywane przez wykwalifikowanych chirurgów w warunkach sali operacyjnej.…”

Section: Methodsunclassified

“…This procedure significantly shortens the healing time, although in Poland it is only reserved for hospitalized patients. It is popular to use a dermatome or specialized equipment for collecting islands of the epidermis [18][19][20][21][22][23][24]. Those methods, however, need to be performed by qualified surgeons in a surgical room.…”

Section: Materiał I Metodymentioning

confidence: 99%

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Assessment of the effect of punch full-thickness skin grafting on wound epithelialization

Nowak¹,

Mehrholz²,

Barańska‐Rybak³

2021

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Introduction: One of the methods to accelerate skin epithelialisation is skin grafting. Various methods of skin transplantations are available, such as full thickness skin transplantation, intermediate-thickness skin transplant using a dermatome, and epidermal islet transplantation using vacuum apparatus an epidermal harvesting system. These methods, however, require the use of specialised and expensive equipment. An alternative is to perform full-thickness skin grafts with a dermatological punch. Objective: The aim of the study was to utilize the new technique of punch grafting and evaluate it's effect on wound healing. Material and methods: Five patients with granulating venous ulcers, which were not infected or cancerous, underwent the procedure. Full thickness punch grafts were placed every 2 cm 2 . Patients were followed up every week for 3 months and assessed for the number of micrografts rejected and percentage of the wound that has epithelialised. We have also noted the VAS pain scale. Results: Reduction in the wound area after 30 days was observed in all patients. In 2 patients, complete resolution was observed. No adverse effects were recorded. Average visual analogue scale (1-10) for pain was 4.4 ±0.927. The procedure took on average 39 ±4.3 minutes. Conclusions:Micrografts have a very high potential to accelerate the epithelialisation of chronic ulcers. Compared to the conventional procedures, they are costeffective and easier to perform. It is an effective method that can be used in outpatient settings.

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Section: Methodsunclassified

Section: Materiał I Metodymentioning

confidence: 99%

Assessment of the effect of punch full-thickness skin grafting on wound epithelialization

Nowak¹,

Mehrholz²,

Barańska‐Rybak³

2021

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“…CelluTome provides a simpler and painless procedure compared to the standard debridement procedures. [132] LumiHeal (BioPhotonic gel) is a nonthermal and noninvasive topical treatment gel based on fluorescent light energy (FLE) technology. [133,134] At a cellular and subcellular level, this gel delivers FLE at a distance of approximately 5 cm.…”

Section: Wound Care Devicesmentioning

confidence: 99%

“…CelluTome provides a simpler and painless procedure compared to the standard debridement procedures. [ 132 ]…”

Section: Commercial Products For Chronic Wounds Treatmentmentioning

confidence: 99%

Updates on Recent Clinical Assessment of Commercial Chronic Wound Care Products

Sharma

Zhao

2023

Adv Healthcare Materials

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Impaired wound healing after trauma, disorders, and surgeries impact millions of people globally every year. Dysregulation in orchestrated healing mechanisms and underlying medical complications make chronic wound management extremely challenging. Besides standard‐of‐care treatments including broad spectrum antibiotics and wound‐debridement, novel adjuvant therapies are clinically tested and commercialized. These include topical agents, skin substitutes, growth factor delivery, and stem cell therapies. With a goal to overcome factors playing pivotal role in delayed wound healing, researchers are exploring novel approaches to elicit desirable healing outcomes in chronic wounds. Although recent innovations in wound care products, therapies, and devices are extensively reviewed in past, a comprehensive review summarizing their clinical outcomes is surprisingly lacking. Herein, this work reviews the commercially available wound care products and their performance in clinical trials to provide a statistically comprehensive understanding of their safety and efficacy. The performance and suitability of various commercial wound care platforms, including xenogeneic and allogenic products, wound care devices, and novel biomaterials, are discussed for chronic wounds. The current clinical evaluation will provide a comprehensive understanding of the benefits and drawbacks of the most‐recent approaches and will enable researchers and healthcare providers to develop next‐generation technologies for chronic wound management.

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Use of Cellutome for the healing of venous or mixed ulcers

Cited by 2 publications

References 13 publications

Assessment of the effect of punch full-thickness skin grafting on wound epithelialization

Assessment of the effect of punch full-thickness skin grafting on wound epithelialization

Updates on Recent Clinical Assessment of Commercial Chronic Wound Care Products

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