Use of autologous platelet-rich plasma in androgenetic alopecia in women: a systematic review and meta-analysis

Oliveira, Antonio Flavio; Arcanjo, Francisco Plácido Nogueira; Rodrigues, Maria Rosineida Paiva; Silva, Ana Augusta Rosa e; Hall, Peter Richard

doi:10.1080/09546634.2022.2138692

Cited by 7 publications

(9 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Review and meta-analysis studies revealed a significant increase in hair density and diameter compared to the baseline/control group. [14][15][16] Similar results were observed in the present study, and the PRP group demonstrated a significant increase in hair density and diameter.…”

Section: Discussionsupporting

confidence: 91%

See 1 more Smart Citation

Evaluation of the effects of adding an adipose tissue‐derived stromal vascular fraction to platelet‐rich plasma injection in the treatment of androgenetic alopecia: A randomized clinical trial

Behrangi,

Rahimi,

Zare

et al. 2024

Skin Research and Technology

View full text Add to dashboard Cite

BackgroundStromal vascular fraction (SVF) cells derived from adipose tissue and platelet‐rich plasma (PRP) are among novel treatments for androgenetic alopecia (AGA). We aimed to investigate the effect of adding SVF to PRP and compare it to administering PRP injection alone.MethodsEighteen patients were randomly divided into two groups of nine. The PRP group was treated with PRP at all three visits at 1‐month intervals, while the SVF‐PRP group received an SVF injection on the first visit and a PRP injection on the second and third visits. Each group was evaluated at baseline and 20 weeks after the therapy's initiation.ResultsChanges in mean hair diameter and hair count compared to baseline were significant in both groups. The PRP group experienced a greater increase in mean hair count than the SVF‐PRP group, and the SVF‐PRP group had a marginally greater increase in hair diameter than the PRP group. These differences were not statistically significant compared to each other. The patient and physician assessment scores exceeded the mean (on a scale from 0: poor to 3: excellent) in both groups.ConclusionAdding one SVF injection to two PRP treatment sessions versus three PRP injections alone had no significant difference in evaluated variables. If additional research demonstrates the same results, we suggest that multiple SVF injection sessions may be required to produce a statistically significant difference compared to PRP injection alone. Moreover, considering lower cost and greater accessibility of PRP, it can be used before SVF in the treatment of AGA.

show abstract

Section: Discussionsupporting

confidence: 91%

“…In line with several studies, 14,15,22 pain during injection and headache being the most common side effects.…”

Section: Discussionsupporting

confidence: 83%

Evaluation of the effects of adding an adipose tissue‐derived stromal vascular fraction to platelet‐rich plasma injection in the treatment of androgenetic alopecia: A randomized clinical trial

Behrangi,

Rahimi,

Zare

et al. 2024

Skin Research and Technology

View full text Add to dashboard Cite

show abstract

Section: Accepted Manuscriptmentioning

confidence: 99%

“…26 Another recent study demonstrated significant hair diameter increases by 27.5% in men and 31.3% in women at 6 months after three PRP injections. 61,[63][64][65] PRP is recommended as an adjunctive therapy to the standard treatment of oral finasteride and topical minoxidil. PRP can be used to treat both male and female AGA with satisfactory results.…”

Section: Nonsurgical Nonmedical Treatmentmentioning

confidence: 99%

“…63 The recommended techniques of PRP treatment for AGA are summarized in ►Table 5. 63,64,66,[70][71][72][73][74] The complications of PRP in most studies are minimal and transient. Injecting local anesthetics to the scalp (e.g., lidocaine with epinephrine) may cause minor pain and burning, local bruising, and local anesthetic reactions (rare).…”

Section: Nonsurgical Nonmedical Treatmentmentioning

confidence: 99%

See 1 more Smart Citation

Medical Treatment for Androgenetic Alopecia

Panchaprateep

2023

Facial Plast Surg

View full text Add to dashboard Cite

Androgenetic alopecia (AGA) is a common type of hair loss, which is generally influenced by genetic factors and systemic androgens resulting in follicular miniaturization1. It can cause cosmetic problems leading to psychological distress among affected men and women. Effective standard medical treatments available are topical minoxidil 2-5%, oral finasteride, oral dutasteride, and hair transplantation.1 However, some patients do not achieve favorable results with standard treatments. For these reasons, other novel treatments have been developed, including new medications, regenerative medicines (autologous platelet-rich plasma (PRP), adipose derived stem cells, micrograft generation and exosome) and low-level laser therapy (LLLT).

show abstract

Is autologous platelet-rich plasma capable of increasing hair density in patients with androgenic alopecia? A systematic review and meta-analysis of randomized clinical trials

Kieling,

Konzen,

Zanella

et al. 2024

Anais Brasileiros de Dermatologia

View full text Add to dashboard Cite

Use of autologous platelet-rich plasma in androgenetic alopecia in women: a systematic review and meta-analysis

Cited by 7 publications

References 31 publications

Evaluation of the effects of adding an adipose tissue‐derived stromal vascular fraction to platelet‐rich plasma injection in the treatment of androgenetic alopecia: A randomized clinical trial

Evaluation of the effects of adding an adipose tissue‐derived stromal vascular fraction to platelet‐rich plasma injection in the treatment of androgenetic alopecia: A randomized clinical trial

Medical Treatment for Androgenetic Alopecia

Is autologous platelet-rich plasma capable of increasing hair density in patients with androgenic alopecia? A systematic review and meta-analysis of randomized clinical trials

Contact Info

Product

Resources

About