2014
DOI: 10.4034/pboci.2014.141.03
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Use of Animal models in Experimental Research in Dentistry in Brazil

Abstract: Objective:To identify the types of animals commonly used in experimental research in dentistry in Brazil. Material and Methods: 2721 studies were evaluated, of which 379 (13.9 %) involved animals. The variables analyzed were: area of knowledge, type of study, type of animal, number of animals, occurrence of sacrifice, body part used and financing. Descriptive and inferential statistical analyses were performed using the chi-square test (p < 0.05) with the SPSS 18.0 software. Results: Research in Dental Materia… Show more

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Cited by 4 publications
(2 citation statements)
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“…The use of animal species is a common practice in dental research, with a predominance of rodents, mainly due to physiological characteristics that may mimic human behavior. Because of the often superiority to in vitro research, a high-quality designed animal model supports future clinical trials in humans ( Bernardino et al, 2014 , Nokhbatolfoghahaei et al, 2020 ).…”
Section: Discussionmentioning
confidence: 99%
“…The use of animal species is a common practice in dental research, with a predominance of rodents, mainly due to physiological characteristics that may mimic human behavior. Because of the often superiority to in vitro research, a high-quality designed animal model supports future clinical trials in humans ( Bernardino et al, 2014 , Nokhbatolfoghahaei et al, 2020 ).…”
Section: Discussionmentioning
confidence: 99%
“…Refine: Refining the way the animals are being taken care of. To help minimise any kind of stress or pain, by using less invasive techniques wherever possible and improving medical care and living conditions for such animal models 3 .Animals have been targets for investigations and observations for mankind.Animal research has been important in the development of many major medical advances. Studies that use animals have played a role in the prevention or treatment of conditions as diverse as tuberculosis, diabetes, polio, parkinson's disease, muscular dystrophy and high blood pressure 4 .…”
Section: These Arementioning
confidence: 99%