“…As described for the first time by Heimdal et al, during myocardial contraction, as the wall shortens, it also thickens, which is used for assessment of contractile function, with radial thickening (positive strain), circumferential shortening (negative strain), and longitudinal shortening (negative strain). At low doses, dobutamine enhances myocardial blood flow in the region served by the narrowed coronary arteries and then enhances myocardial contractility and improves segmental wall motion …”