The detection of viable myocardium by low‐dose dobutamine stress speckle tracking echocardiography in patients with old myocardial infarction

Liang, Li; Wang, Fengli; Xu, Tongda; Chen, Junhong; Wang, Chaofan; Wang, Xiaoping; Li, Dongye

doi:10.1002/jcu.22366

Cited by 11 publications

(13 citation statements)

References 32 publications

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“…Seventythree percent have their total cholesterol >250 mg /dl, and 60% was a smoker. These findings were expected in those ischemic heart disease patients as the mentioned risk factor is common in these selected patients (Li et al, 2016). Revascularization has become an important therapeutic strategy for patients with old MI.…”

Section: Discussionsupporting

confidence: 53%

Evaluation of patients with myocardial infarction undergoing percutaneous coronary intervention (PCI) using low dose dobutamine stress echocardiography

Jabir¹,

Hasan²,

Jumaah³

et al. 2019

ijrps

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Coronary artery disease (CAD) is a spectrum of heart diseases which has the highest mortality in the world. Systolic left ventricular (LV) function is an important predictor of outcome, and its precise assessment remains of great importance for the choice of treatment in populations with myocardial infarction (MI). This study was aimed to assess the function and viability of ischemic myocardium of LV before and after the percutaneous coronary intervention (PCI) by using 2dimentional (2D) STE with LDDSE and to know the usefulness of low dose dobutamine (LDD) test in detecting the viable ischemic LV area. The results of the current study revealed there was a significant decrease (improvement) in GLS before dobutamine from (-10.49±3.4) to (-12.87±3.44) after dobutamine. Then there was a significant increase (deterioration) in GLS from (-12.87±3.44) after giving 5 mg/kg/min dobutamine to (-11.56±3.29) after giving 10 mg/kg/min dobutamine (P value < 0.001). While there were no significant differences in GLS after low dose dobutamine (-12.87±3.44) with the same parameters 3-6 months after PCI (-13.48±3.7). Left anterior descending artery (LAD) is the most common affected artery in our study. The study concluded that GLS provides a sensitive measure of LV function and appears reduced despite preserved LVEF also GLS can detect the viability of ischemic myocardium of LV with using LDD test which then assessed by PCI.

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Section: Discussionsupporting

confidence: 53%

Evaluation of patients with myocardial infarction undergoing percutaneous coronary intervention (PCI) using low dose dobutamine stress echocardiography

Jabir¹,

Hasan²,

Jumaah³

et al. 2019

ijrps

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“…[29,30] 2D-STE is used to evaluate VM by measuring the LV global and regional strain and strain rate recently. [31,32] Some studies have shown that 2D-STE has high sensitivity and appropriate specificity for early identification of VM in patients with AMI by strain and strain rate measurements. [33]…”

Section: Discussionmentioning

confidence: 99%

Evaluation of myocardial viability in patients with acute myocardial infarction

et al. 2019

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Background:The value of layer-specific two-dimensional speckle tracking echocardiography (LS2D-STE) for evaluating viable myocardium (VM) in patients with acute myocardial infarction (AMI) was unclear, this study provides new insights into it and to make a comparison with dualisotope simultaneous acquisition single photon emission computed tomography ( DISA-SPECT).Methods:Forty hospitalized patients with AMI and left ventricular systolic dysfunction (left ventricular ejection fraction <50%) underwent LS2D-STE and DISA-SPECT before percutaneous coronary intervention (PCI). The longitudinal, circumferential, and radial peak systolic strains and the peak systolic strain rates of 3 myocardiallayers (endocardium, mid-myocardium, and epicardium), as well as the total wall thickness, were determined by LS2D-STE. Routine echocardiography was followedup at 1, 3, 6 months after PCI, with the improvement of the wall motion as the goldenstandard for evaluating VM.Results:The sensitivity, specificity and accuracy of DISA-SPECT for evaluating VM were 82.1%, 74.3%, and 79.3%, respectively. Among the layer-specific parameters, only endocardial (endo-) longitudinal strain (LS) and endo- longitudinal strain rate (LSr) were used as independent parameters for evaluating VM (P < .05), and the sensitivity, specificity and accuracy of endo-LS and endo-LSr in evaluation of VM were 77.1%, 65.4%, and 72.9% vs 72.9%, 65.4%, and 69.7%. Endo-LS and endo-LSr were superior to total wall thickness LS and LSr (AUC endo-LS 0.767 vs total-LS 0.669; endo-LSr 0.743 vs total-LSr 0.682). The parallel test and the serial test of combination of endo-LS and endo-LSr showed similar sensitivity, specificity and accuracy to DISA-SPECT (P > .05).Conclusion:The endo-LS and endo-LSr analysis of LS2D-STE can evaluate the VM well, and its sensitivity, specificity and accuracy in detection of VM are similar to those of DISA-SPECT, resulting in LS2D-STE being a good option for the assessment of VM.

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“…The combination of low‐dose dobutamine stress echo (LDDSE) and STI has been used for detection of viable myocardium in patients with old myocardial infarction. In a recent study LS at LDDSE was superior to semiquantitative wall‐motion analysis with LDDSE for the assessment of viable myocardium. In the multivariable analysis LS combined with LSR was considered as an independent predictor of viable myocardium and LVEF was improved after PCI in these patients.…”

Section: Deformation Imaging In Ischemic Cardiomyopathymentioning

confidence: 97%

Role of the deformation imaging in the evaluation of patients with cardiomyopathy

Papadopoulos

2017

Continuing Cardiol Educ

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Cardiomyopathies are a heterogeneous group of diseases recognized by specific patterns of myocardial morphology and function. Myocardial deformation imaging, using strain and strain rate as main parameters, is a novel echocardiographic method for the evaluation of global and regional myocardial function. Speckle tracking imaging is currently the best technique for the evaluation of myocardial deformation in the longitudinal, radial, and circumferential axis. The aim of the following review was to analyze the potential role of the deformation imaging in the evaluation of cardiomyopathies, focusing on the recent developments regarding the differential and early diagnosis as well as the prognosis of the disease.

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The detection of viable myocardium by low‐dose dobutamine stress speckle tracking echocardiography in patients with old myocardial infarction

Cited by 11 publications

References 32 publications

Evaluation of patients with myocardial infarction undergoing percutaneous coronary intervention (PCI) using low dose dobutamine stress echocardiography

Evaluation of patients with myocardial infarction undergoing percutaneous coronary intervention (PCI) using low dose dobutamine stress echocardiography

Evaluation of myocardial viability in patients with acute myocardial infarction

Role of the deformation imaging in the evaluation of patients with cardiomyopathy

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