Use of Amniotic Membrane Graft in Glaucoma Shunt Surgery

Anand, Aashish; Sheha, Hosam; Teng, Christopher C.; Liebmann, Jeffrey M.; Ritch, Robert; Tello, Celso

doi:10.3928/15428877-20110426-01

Cited by 31 publications

(31 citation statements)

References 30 publications

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“…Similar to AM, cryopreserved UCP also exerts therapeutic actions [18]. It is easier to handle [19] and has already been successfully used for the glaucoma shunt tubes covering [20] and conjunctival surface reconstruction [19]. …”

Section: Introductionmentioning

confidence: 99%

Umbilical Cord Patch Transplantation for Corneal Perforations and Descemetoceles

Xie

Zhao

Liu

et al. 2017

Journal of Ophthalmology

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Purpose To evaluate the clinical outcome of umbilical cord patch (UCP) transplantation for deep corneal ulcers with perforations and descemetoceles. Methods In this retrospective, noncomparative, interventional case series, 11 eyes of 11 patients with corneal perforation or descemetocele were included. The thickness and microstructure of UCP were measured. All eyes were treated with UCP and amniotic membrane transplantation for corneal reconstruction. Corneal ulcer healing, corneal thickness, anterior chamber formation, and best-corrected visual acuity (BCVA) were recorded and analyzed. Results The thickness of human UCP is 398.6 ± 102.8 μm (n = 5) with compact aligned fibers. The average age was 56.2 ± 15.8 (ranging from 22 to 75) years. The mean follow-up period was 7.1 ± 1.7 (ranging from 5 to 10) months. Four patients had descemetocele and 7 had perforation. The anterior chambers in all the 7 perforated corneas were formed at postoperative day 1. All patients regained a normal corneal thickness and smooth corneal surface within the first postoperative month. The vision improved in 10 eyes and remained unchanged in 1 eye. No recurrence nor side effects occurred during the follow-up. Conclusions UCP can serve as an alternative material in the treatment of corneal perforations and descemetoceles. This treatment option is also beneficial in those countries with limited cornea donors and eye bank services.

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Section: Introductionmentioning

confidence: 99%

Umbilical Cord Patch Transplantation for Corneal Perforations and Descemetoceles

Xie

Zhao

Liu

et al. 2017

Journal of Ophthalmology

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“…We have gathered preliminary data supporting the feasibility of using anterior segment optic coherence tomography (OCT) to detect the presence of AM and the evidence of host cell integration into the AM after being transplanted in the subconjunctival space to cover the glaucoma shunt tube. Our results showed that implanted AM maintained its thickness over a period of 12 months (Anand et al, 2011).…”

Section: Potential Advantages Of Ammentioning

confidence: 49%

Update on Modulating Wound Healing in Trabeculectomy

Sheha¹

2011

Glaucoma - Basic and Clinical Concepts

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“…The risk of infection [1, 2] and progressive exposure dictates prompt surgical intervention [3]. Different materials, including buccal mucosa [3], pericardium [4], human sclera [5], dura [6], and cornea [7], have been used to prevent exposure but none with universal success. In addition, there are several disadvantages particular to each material.…”

Section: Introductionmentioning

confidence: 99%

Short-Term Outcomes of KeraSys Patch Graft for Glaucoma Drainage Devices: A Case Series

Nagi

Cumba

Bell

et al. 2013

Journal of Ophthalmology

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Purpose. Tube-related exposure is a known complication of glaucoma drainage device (GDD) surgery. Our objective is to report the early (approximately 1 year) tube exposure rate of implants covered with a keraSys (IOP Inc., Costa Mesa, CA, USA) tissue reinforcement graft. Patients and Methods. A retrospective, noncomparative, consecutive case series of 42 eyes with GDD implantation with keraSys patch grafts was performed. Main outcome measurements included patch-related complications: patch exposure, tube exposure, wound dehiscence, and patch migration. Results. Forty-two eyes were followed for an average of 15.24 ± 10.44 months (range 1.0–32.3 months). Four (10%) eyes experienced patch-related complications: two with exposure 8 months postoperatively, one with exposure 13 months postoperatively, and one with exposure 4 weeks postoperatively. Conclusion. The effectiveness of the keraSys patch graft is limited by the higher than expected early exposure rate found in this case series. These results should be confirmed in other studies.

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Use of Amniotic Membrane Graft in Glaucoma Shunt Surgery

Abstract: Amniotic membrane graft offers good tectonic support and allows direct visualization of the underlying tube.

Cited by 31 publications

References 30 publications

Umbilical Cord Patch Transplantation for Corneal Perforations and Descemetoceles

Umbilical Cord Patch Transplantation for Corneal Perforations and Descemetoceles

Update on Modulating Wound Healing in Trabeculectomy

Short-Term Outcomes of KeraSys Patch Graft for Glaucoma Drainage Devices: A Case Series

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