The advance of online technology and instructional delivery such as Web-based learning (WBL) has heralded new changes in education. Students using the WBL environment in various courses at eight universities in Malaysia were surveyed. Results showed that five main factors influence the effectiveness of the online learning process: students' behavior, characteristics of lecturers, interactive application, technology or system, and the institutions. Results indicated that students' grades are highly correlated with student perception, self-efficacy and interactivity. The WBL learners do not outperform traditional learners. There is also a need to improve the quality of WBL due to differences in adaptation styles of learners in the process.