SU-8 is an epoxy-novolac resin and a well-established negative photoresist for microfabrication and
microengineering. The photopolymerized resist is an extremely highly crosslinked polymer showing
outstanding chemical and physical robustness with residual surface epoxy groups amenable for chemical
functionalization. In this paper we describe, for the first time, the preparation and surface modification of
SU-8 particles shaped as microbars, the attachment of appropriate linkers, and the successful application of
these particles to multistep solid-phase synthesis leading to oligonucleotides and peptides attached in an
unambiguous manner to the support surface.