Use of a Non-Crosslinked Porcine Dermal Matrix in Repair of the Achilles and Other Tendons of the Foot

Anaim, Ali

doi:10.1177/1938640017751189

Cited by 5 publications

(6 citation statements)

References 27 publications

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“…The use of a cellular-free dermal matrix to augment Achilles tendon repairs has been proposed, either using human [40][41][42] or porcine membranes, 43 with excellent results. Brandeisky and Pelan 44 proposed the use of viable intact cryopreserved umbilical tissue, with encouraging results.…”

Section: Discussionmentioning

confidence: 99%

Microfragmented Adipose Tissue (M-FATS) for Improved Healing of Surgically Repaired Achilles Tendon Tears: A Preliminary Study

Ferracini

Artiaco

Daghino

et al. 2020

Foot & Ankle Specialist

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Introduction Tendon healing is a complicated process that results in inferior structural and functional properties when compared with healthy tendon; the purpose of this study was to assess the effects of the adjunct of microfragmented adipose tissue (M-FATS) after the suture of a series of Achilles tendons. Methods After complete Achilles tendon tear, 8 patients underwent open suture repair in conjunction with perilesional application of a preparation of M-FATS rich in mesenchymal stem cells. Results were compared with a similar group of patients treated with conventional open suture. Outcomes were evaluated based on range of motion, functional recovery, and complications according to the American Orthopedic Foot and Ankle Society (AOFAS) score and Foot and Ankle Disability Index (FADI). Achilles tendons were examined by ultrasound (US) at 3 months. Results The AOFAS and FADI scores showed no differences between the 2 groups. US evaluation showed quicker tendon remodeling in the M-FATS group. Adverse events were not documented for both procedures. Conclusions The combined application of derived M-FATS for tendon rupture is safe and presents new possibilities for enhanced healing. Levels of Evidence Level IIIb: Case control study

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Section: Discussionmentioning

confidence: 99%

Microfragmented Adipose Tissue (M-FATS) for Improved Healing of Surgically Repaired Achilles Tendon Tears: A Preliminary Study

Ferracini

Artiaco

Daghino

et al. 2020

Foot & Ankle Specialist

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“…Its use is especially beneficial in chronic and complex injuries but there is still not enough evidence to conclude augmentation's superiority over traditional methods. [49] The rotator cuff is another focus in orthobiologic augmentation. Platelet-rich plasma, biologic matrix augmentation, synthetic scaffolds, growth factors, and stem cells are the most studied topics in rotator cuff tears.…”

Section: Bonementioning

confidence: 99%

Are orthobiologics the next chapter in clinical orthopedics? A literature review

Sezgin

Atik²

2018

Eklem Hastalik Cerrahisi

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Orthobiologics are biologically derived materials which aim to promote healing and regeneration of tissues that are the focus of orthopedic surgery. Since bones, ligaments, tendons, and cartilage have different healing and regeneration characteristics, treatment strategies and clinical problems related to these tissues greatly differ. Although orthobiolgics are an old concept, most of the advancements in this field have been accomplished within the last two decades. A large number of promising laboratory studies show that orthobiolics hold a great potential in launching the next chapter of orthopedics. In this article, the use, research on this subject, future potential of orthobiologics, and the tissues in focus have been briefly reviewed.

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“…These scaffolds are mostly mammalian-derived, including decellularized human, porcine, bovine, and equine tendon sheets, dermis, pericardium, small intestinal submucosa, etc. [ [15] , [16] , [17] , [18] , [19] ]. However, these mammal-derived decellularized ECMs have limitations such as limited donor sources, the potential risk of zoonotic diseases, and ethical and religious issues [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Decellularized tilapia fish skin: A novel candidate for tendon tissue engineering

Liu

Peng

et al. 2022

Materials Today Bio

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Use of a Non-Crosslinked Porcine Dermal Matrix in Repair of the Achilles and Other Tendons of the Foot

Abstract: Level IV: Case series.

Cited by 5 publications

References 27 publications

Microfragmented Adipose Tissue (M-FATS) for Improved Healing of Surgically Repaired Achilles Tendon Tears: A Preliminary Study

Microfragmented Adipose Tissue (M-FATS) for Improved Healing of Surgically Repaired Achilles Tendon Tears: A Preliminary Study

Are orthobiologics the next chapter in clinical orthopedics? A literature review

Decellularized tilapia fish skin: A novel candidate for tendon tissue engineering

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